WEKO3
アイテム
{"_buckets": {"deposit": "5c570eda-ea71-458f-99a7-7d447cb7e87b"}, "_deposit": {"created_by": 3, "id": "14004", "owners": [3], "pid": {"revision_id": 0, "type": "depid", "value": "14004"}, "status": "published"}, "_oai": {"id": "oai:kindai.repo.nii.ac.jp:00014004", "sets": ["2672"]}, "author_link": ["25710", "25709", "25707", "25708"], "item_8_alternative_title_3": {"attribute_name": "その他(別言語等)のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Regional glucose metabolic reduction in dementia with Lewy bodies is independent of amyloid deposition"}]}, "item_8_biblio_info_21": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2013-01-01", "bibliographicIssueDateType": "Issued"}, "bibliographicPageEnd": "5", "bibliographicPageStart": "1", "bibliographic_titles": [{"bibliographic_title": "科学研究費助成事業研究成果報告書 (2013. )"}]}]}, "item_8_description_33": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "研究成果の概要(和文): アミロイドイメージングと糖代謝画像を用いてアルツハイマー病(AD)についで多いレビー小体型認知症(DLB)の病態につき検討した. DLB群では半数がアミロイド沈着陽性, 残り半数が陰性であったが, 糖代謝はアミロイド沈着に依存せずAD群と比較して後頭葉, 頭頂側頭連合野, 後部帯状回・楔前部で有意に低いことを確認した. 研究成果の概要(英文): The purpose of this study was to clarify whether regional hypometabolism is related to amyloid deposits in the dementia with Lewy bodies (DLB) brain. Methods: Ten consecutive subjects with DLB and 10 Alzheimer disease (AD) patients who underwent both PiB-PET and FDG-PET were included in this study. Regional standardized uptake value ratio (SUVR)s normalised to cerebellar cortices were calculated in the FDG and PiB PET images. Results: All AD patients and five DLB patients showed amyloid deposits (PiB positive). The parietotemporal and occipital metabolism in the DLB group were significantly lower than those in the AD group. In DLB patients, there were no differences in regional glucose metabolism between PiB positive and negative patients. Conclusions: In the DLB brain, decreased regional glucose metabolism is unrelated to amyloid deposits, although the hypometabolic area overlaps with the AD hypometabolic area.", "subitem_description_type": "Abstract"}]}, "item_8_description_36": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "研究種目:基盤研究(C); 研究期間:2011~2013; 課題番号:23591804; 研究分野:臨床; 科研費の分科・細目:核医学", "subitem_description_type": "Other"}]}, "item_8_description_37": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"subitem_description": "Research Paper", "subitem_description_type": "Other"}]}, "item_8_description_41": {"attribute_name": "フォーマット", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_8_publisher_14": {"attribute_name": "出版者 名前", "attribute_value_mlt": [{"subitem_publisher": "近畿大学"}]}, "item_8_relation_11": {"attribute_name": "著者 外部リンク", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "http://kaken.nii.ac.jp/d/r/50534103.ja.html"}]}, {"subitem_relation_name": [{"subitem_relation_name_text": "http://kaken.nii.ac.jp/d/r/20252653.ja.html"}]}, {"subitem_relation_name": [{"subitem_relation_name_text": "http://kaken.nii.ac.jp/d/r/20296700.ja.html"}]}, {"subitem_relation_name": [{"subitem_relation_name_text": "http://kaken.nii.ac.jp/d/r/70335339.ja.html"}]}]}, "item_8_text_10": {"attribute_name": "著者 役割", "attribute_value_mlt": [{"subitem_text_value": "研究代表者"}, {"subitem_text_value": "研究分担者"}, {"subitem_text_value": "研究分担者"}, {"subitem_text_value": "研究分担者"}]}, "item_8_text_15": {"attribute_name": "出版社 カナ", "attribute_value_mlt": [{"subitem_text_value": "キンキ ダイガク"}]}, "item_8_text_16": {"attribute_name": "出版社 ローマ字", "attribute_value_mlt": [{"subitem_text_value": "Kinki Daigaku"}]}, "item_8_text_17": {"attribute_name": "出版年(from)", "attribute_value_mlt": [{"subitem_text_value": "2014"}]}, "item_8_text_44": {"attribute_name": "ID(XooNIps)", "attribute_value_mlt": [{"subitem_text_value": "KAKEN_23591804seika"}]}, "item_8_text_47": {"attribute_name": "日付 記録日(XooNIps)", "attribute_value_mlt": [{"subitem_text_value": "2014-10-8"}]}, "item_8_text_51": {"attribute_name": "最終更新日(XooNIps)", "attribute_value_mlt": [{"subitem_text_value": "Oct 16, 2014 09:00:00"}]}, "item_8_text_53": {"attribute_name": "登録者(XooNIps)", "attribute_value_mlt": [{"subitem_text_value": "kurepo"}]}, "item_8_text_54": {"attribute_name": "閲覧数(XooNIps)", "attribute_value_mlt": [{"subitem_text_value": "67"}]}, "item_8_text_55": {"attribute_name": "ダウンロード数(XooNIps)", "attribute_value_mlt": [{"subitem_text_value": "78"}]}, "item_8_text_56": {"attribute_name": "XooNIps_ITEM_KEY", "attribute_value_mlt": [{"subitem_text_value": "17240"}]}, "item_8_text_7": {"attribute_name": "著者(英)", "attribute_value_mlt": [{"subitem_text_language": "en", "subitem_text_value": "ISHII, Kazunari"}, {"subitem_text_language": "en", "subitem_text_value": "MURAKAMI, Takamichi"}, {"subitem_text_language": "en", "subitem_text_value": "OKADA, Masahiro"}, {"subitem_text_language": "en", "subitem_text_value": "KUMANO, Seishi"}]}, "item_8_text_8": {"attribute_name": "著者 所属", "attribute_value_mlt": [{"subitem_text_value": "近畿大学医学部; 教授近畿大学医学部; 教授近畿大学医学部; 講師近畿大学医学部; 講師"}]}, "item_8_version_type_12": {"attribute_name": "版", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "石井, 一成"}, {"creatorName": "イシイ, カズナリ", "creatorNameLang": "ja-Kana"}], "nameIdentifiers": [{"nameIdentifier": "25707", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "70335339", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": " "}]}, {"creatorNames": [{"creatorName": "村上, 卓道"}, {"creatorName": "ムラカミ, タカミチ", "creatorNameLang": "ja-Kana"}], "nameIdentifiers": [{"nameIdentifier": "25708", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "岡田, 真広"}, {"creatorName": "オカダ, マサヒロ", "creatorNameLang": "ja-Kana"}], "nameIdentifiers": [{"nameIdentifier": "25709", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "熊野, 正士"}, {"creatorName": "クマノ, セイシ", "creatorNameLang": "ja-Kana"}], "nameIdentifiers": [{"nameIdentifier": "25710", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2016-03-31"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KAKEN_23591804seika.pdf", "filesize": [{"value": "226.9 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 226900.0, "url": {"label": "KAKEN_23591804seika.pdf", "url": "https://kindai.repo.nii.ac.jp/record/14004/files/KAKEN_23591804seika.pdf"}, "version_id": "2e57932f-d429-4eaf-aa7c-89f3d14cebcb"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "認知症", "subitem_subject_scheme": "Other"}, {"subitem_subject": "レビー小体型認知症", "subitem_subject_scheme": "Other"}, {"subitem_subject": "PET", "subitem_subject_scheme": "Other"}, {"subitem_subject": "アミロイド", "subitem_subject_scheme": "Other"}, {"subitem_subject": "糖代謝", "subitem_subject_scheme": "Other"}, {"subitem_subject": "脳", "subitem_subject_scheme": "Other"}, {"subitem_subject": "アルツハイマー病", "subitem_subject_scheme": "Other"}, {"subitem_subject": "パーキンソン病", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "research report", "resourceuri": "http://purl.org/coar/resource_type/c_18ws"}]}, "item_title": "レビー小体型認知症におけるアミロイド沈着, 糖代謝病態解明", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "レビー小体型認知症におけるアミロイド沈着, 糖代謝病態解明"}]}, "item_type_id": "8", "owner": "3", "path": ["2672"], "permalink_uri": "https://kindai.repo.nii.ac.jp/records/14004", "pubdate": {"attribute_name": "公開日", "attribute_value": "2014-10-16"}, "publish_date": "2014-10-16", "publish_status": "0", "recid": "14004", "relation": {}, "relation_version_is_last": true, "title": ["レビー小体型認知症におけるアミロイド沈着, 糖代謝病態解明"], "weko_shared_id": -1}
レビー小体型認知症におけるアミロイド沈着, 糖代謝病態解明
https://kindai.repo.nii.ac.jp/records/14004
https://kindai.repo.nii.ac.jp/records/1400402031ce2-79ad-4cfa-9343-73aece0c0752
名前 / ファイル | ライセンス | アクション |
---|---|---|
KAKEN_23591804seika.pdf (226.9 kB)
|
|
Item type | 研究報告書 / Research Paper(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2014-10-16 | |||||
タイトル | ||||||
タイトル | レビー小体型認知症におけるアミロイド沈着, 糖代謝病態解明 | |||||
その他(別言語等)のタイトル | ||||||
その他のタイトル | Regional glucose metabolic reduction in dementia with Lewy bodies is independent of amyloid deposition | |||||
著者 |
石井, 一成
× 石井, 一成× 村上, 卓道× 岡田, 真広× 熊野, 正士 |
|||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題 | 認知症, レビー小体型認知症, PET, アミロイド, 糖代謝, 脳, アルツハイマー病, パーキンソン病 | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_18ws | |||||
資源タイプ | research report | |||||
著者(英) | ||||||
en | ||||||
ISHII, Kazunari | ||||||
著者(英) | ||||||
en | ||||||
MURAKAMI, Takamichi | ||||||
著者(英) | ||||||
en | ||||||
OKADA, Masahiro | ||||||
著者(英) | ||||||
en | ||||||
KUMANO, Seishi | ||||||
著者 所属 | ||||||
近畿大学医学部; 教授近畿大学医学部; 教授近畿大学医学部; 講師近畿大学医学部; 講師 | ||||||
著者 役割 | ||||||
研究代表者 | ||||||
著者 役割 | ||||||
研究分担者 | ||||||
著者 役割 | ||||||
研究分担者 | ||||||
著者 役割 | ||||||
研究分担者 | ||||||
著者 外部リンク | ||||||
関連名称 | http://kaken.nii.ac.jp/d/r/50534103.ja.html | |||||
著者 外部リンク | ||||||
関連名称 | http://kaken.nii.ac.jp/d/r/20252653.ja.html | |||||
著者 外部リンク | ||||||
関連名称 | http://kaken.nii.ac.jp/d/r/20296700.ja.html | |||||
著者 外部リンク | ||||||
関連名称 | http://kaken.nii.ac.jp/d/r/70335339.ja.html | |||||
版 | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 名前 | ||||||
出版者 | 近畿大学 | |||||
書誌情報 |
科学研究費助成事業研究成果報告書 (2013. ) p. 1-5, 発行日 2013-01-01 |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 研究成果の概要(和文): アミロイドイメージングと糖代謝画像を用いてアルツハイマー病(AD)についで多いレビー小体型認知症(DLB)の病態につき検討した. DLB群では半数がアミロイド沈着陽性, 残り半数が陰性であったが, 糖代謝はアミロイド沈着に依存せずAD群と比較して後頭葉, 頭頂側頭連合野, 後部帯状回・楔前部で有意に低いことを確認した. 研究成果の概要(英文): The purpose of this study was to clarify whether regional hypometabolism is related to amyloid deposits in the dementia with Lewy bodies (DLB) brain. Methods: Ten consecutive subjects with DLB and 10 Alzheimer disease (AD) patients who underwent both PiB-PET and FDG-PET were included in this study. Regional standardized uptake value ratio (SUVR)s normalised to cerebellar cortices were calculated in the FDG and PiB PET images. Results: All AD patients and five DLB patients showed amyloid deposits (PiB positive). The parietotemporal and occipital metabolism in the DLB group were significantly lower than those in the AD group. In DLB patients, there were no differences in regional glucose metabolism between PiB positive and negative patients. Conclusions: In the DLB brain, decreased regional glucose metabolism is unrelated to amyloid deposits, although the hypometabolic area overlaps with the AD hypometabolic area. | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 研究種目:基盤研究(C); 研究期間:2011~2013; 課題番号:23591804; 研究分野:臨床; 科研費の分科・細目:核医学 | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | Research Paper | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf |