@techreport{oai:kindai.repo.nii.ac.jp:00014004,
 author = {石井,  一成 and 村上,  卓道 and 岡田,  真広 and 熊野,  正士},
 month = {Jan},
 note = {研究成果の概要（和文): アミロイドイメージングと糖代謝画像を用いてアルツハイマー病(AD)についで多いレビー小体型認知症(DLB)の病態につき検討した. DLB群では半数がアミロイド沈着陽性, 残り半数が陰性であったが, 糖代謝はアミロイド沈着に依存せずAD群と比較して後頭葉, 頭頂側頭連合野, 後部帯状回・楔前部で有意に低いことを確認した.           研究成果の概要（英文): The purpose of this study was to clarify whether regional hypometabolism is related to amyloid deposits in the dementia with Lewy bodies (DLB) brain. Methods: Ten consecutive subjects with DLB and 10 Alzheimer disease (AD) patients who underwent both PiB-PET and FDG-PET were included in this study. Regional standardized uptake value ratio (SUVR)s normalised to cerebellar cortices were calculated in the FDG and PiB PET images. Results: All AD patients and five DLB patients showed amyloid deposits (PiB positive). The parietotemporal and occipital metabolism in the DLB group were significantly lower than those in the AD group. In DLB patients, there were no differences in regional glucose metabolism between PiB positive and negative patients. Conclusions: In the DLB brain, decreased regional glucose metabolism is unrelated to amyloid deposits, although the hypometabolic area overlaps with the AD hypometabolic area., 研究種目：基盤研究(C);  研究期間：2011～2013;   課題番号：23591804;   研究分野：臨床;   科研費の分科・細目：核医学, application/pdf},
 title = {レビー小体型認知症におけるアミロイド沈着, 糖代謝病態解明},
 year = {2013},
 yomi = {イシイ, カズナリ and ムラカミ, タカミチ and オカダ, マサヒロ and クマノ, セイシ}
}