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加齢黄斑変性の重症度と動脈硬化の定量的評価
https://kindai.repo.nii.ac.jp/records/23294
https://kindai.repo.nii.ac.jp/records/232941f952876-80ae-4fcc-a2c1-c673453e5d2b
名前 / ファイル | ライセンス | アクション |
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Item type | 研究報告書 / Research Paper(1) | |||||
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公開日 | 2022-12-05 | |||||
タイトル | ||||||
言語 | ja | |||||
タイトル | 加齢黄斑変性の重症度と動脈硬化の定量的評価 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Association between severity of age-related macular degeneration and systemic atherosclerosis | |||||
著者 |
眞野, 福太郎
× 眞野, 福太郎 |
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言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題 | 加齢黄斑変性, ドルーゼン, reticular pseudodrusen, 頚動脈エコー, 動脈硬化 | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_18ws | |||||
資源タイプ | research report | |||||
著者(英) | ||||||
en | ||||||
Mano, Fukutaro | ||||||
著者 所属 | ||||||
近畿大学医学部; 助教 | ||||||
著者所属(翻訳) | ||||||
Kindai University | ||||||
著者 役割 | ||||||
研究代表者 | ||||||
版 | ||||||
出版タイプ | NA | |||||
出版タイプResource | http://purl.org/coar/version/c_be7fb7dd8ff6fe43 | |||||
出版者 名前 | ||||||
出版者 | 近畿大学 | |||||
書誌情報 |
科学研究費助成事業研究成果報告書 (2021) p. 1-4, 発行日 2021 |
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リンクURL | ||||||
内容記述タイプ | Other | |||||
内容記述 | https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20K18400/ | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 研究成果の概要(和文):本研究では加齢黄斑変性の早期進行に関連するとされるreticular pseudodrusen(RPD)に着目し、頚動脈エコーにおける内頚動脈の内膜中膜複合体肥厚度(Max-IMT)や血管の硬化度(血管抵抗指数)の評価を行う研究を行った。加齢黄斑変性の病型とMax-IMTに有意差を認めなかったが、RPDを認める群では有意に血管抵抗指数が高く、すなわち動脈硬化性変化が大きい結果であった。RPDは脂質に関連した変化よりむしろ、血管硬化・線維化に関連する病態である可能性が示唆された。 研究成果の概要(英文): This study focused on reticular pseudodrusen (RPD), which is believed to be associated with early progression of age-related macular degeneration, and conducted a study to evaluate the degree of intima-media complex thickening (Max-IMT) and vascular stiffness (vascular resistance index) of the inner carotid artery on carotid Doppler echography. Although there was no significant difference between age-related macular degeneration and Max-IMT, the group with RPD had a significantly higher vascular resistance index, suggesting that RPD may be a pathological condition related to vascular stiffness and fibrosis rather than lipid-related changes. |
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内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 研究種目:若手研究; 研究期間:2020~2021; 課題番号:20K18400; 研究分野:網膜硝子体; 科研費の分化・細目: | |||||
資源タイプ(WEKO2) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Research Paper | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf |