{"created":"2023-06-20T16:50:43.956887+00:00","id":23294,"links":{},"metadata":{"_buckets":{"deposit":"c05d1ccd-cab1-4d03-9b73-3744bca14b16"},"_deposit":{"created_by":3,"id":"23294","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"23294"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00023294","sets":["14:2667:4819"]},"author_link":["43505"],"control_number":"23294","item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"4","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費助成事業研究成果報告書 (2021)"}]}]},"item_8_description_25":{"attribute_name":"リンクURL","attribute_value_mlt":[{"subitem_description":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20K18400/","subitem_description_type":"Other"}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：本研究では加齢黄斑変性の早期進行に関連するとされるreticular pseudodrusen（RPD）に着目し、頚動脈エコーにおける内頚動脈の内膜中膜複合体肥厚度（Max-IMT）や血管の硬化度（血管抵抗指数）の評価を行う研究を行った。加齢黄斑変性の病型とMax-IMTに有意差を認めなかったが、RPDを認める群では有意に血管抵抗指数が高く、すなわち動脈硬化性変化が大きい結果であった。RPDは脂質に関連した変化よりむしろ、血管硬化・線維化に関連する病態である可能性が示唆された。\n研究成果の概要（英文）： This study focused on reticular pseudodrusen (RPD), which is believed to be associated with early progression of age-related macular degeneration, and conducted a study to evaluate the degree of intima-media complex thickening (Max-IMT) and vascular stiffness (vascular resistance index) of the inner carotid artery on carotid Doppler echography. Although there was no significant difference between age-related macular degeneration and Max-IMT, the group with RPD had a significantly higher vascular resistance index, suggesting that RPD may be a pathological condition related to vascular stiffness and fibrosis rather than lipid-related changes.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目：若手研究; 研究期間：2020～2021; 課題番号：20K18400; 研究分野：網膜硝子体; 科研費の分化・細目：","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ(WEKO2)","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Mano, Fukutaro"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学医学部; 助教"}]},"item_8_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"Kindai University"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"眞野, 福太郎"},{"creatorName":"マノ, フクタロウ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-12-05"}],"displaytype":"detail","filename":"20K18400seika.pdf","filesize":[{"value":"310.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"20K18400seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/23294/files/20K18400seika.pdf"},"version_id":"bb26ad70-8ffc-4237-8c29-3d9dcfbaf880"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"加齢黄斑変性","subitem_subject_scheme":"Other"},{"subitem_subject":"ドルーゼン","subitem_subject_scheme":"Other"},{"subitem_subject":"reticular pseudodrusen","subitem_subject_scheme":"Other"},{"subitem_subject":"頚動脈エコー","subitem_subject_scheme":"Other"},{"subitem_subject":"動脈硬化","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"加齢黄斑変性の重症度と動脈硬化の定量的評価","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"加齢黄斑変性の重症度と動脈硬化の定量的評価","subitem_title_language":"ja"},{"subitem_title":"Association between severity of age-related macular degeneration and systemic atherosclerosis","subitem_title_language":"en"}]},"item_type_id":"8","owner":"3","path":["4819"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-12-05"},"publish_date":"2022-12-05","publish_status":"0","recid":"23294","relation_version_is_last":true,"title":["加齢黄斑変性の重症度と動脈硬化の定量的評価"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-08-02T03:01:03.135409+00:00"}