{"created":"2023-06-20T16:39:51.431545+00:00","id":9993,"links":{},"metadata":{"_buckets":{"deposit":"72c60394-a3bc-48c4-8df1-acbfb65caa53"},"_deposit":{"created_by":3,"id":"9993","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"9993"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00009993","sets":["14:923:2219:2231","21:3039:3435:3436"]},"author_link":["18243","18248","18241","18247","18242","18240","18245","18244","18239","18246"],"item_2_alternative_title_3":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"The discussion on the target protein of histone deacetylase for reprogramming."}]},"item_2_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-03-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"15","bibliographicPageEnd":"7","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"Memoirs of Institute of Advanced Technology, Kinki University"},{"bibliographic_title":"近畿大学先端技術総合研究所紀要","bibliographic_titleLang":"en"}]}]},"item_2_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Somatic cell nuclear transfer technology enables somatic cells to achieve totipotency. In addition, pluripotency is acquired by introduction of only four transcriptional factors（Oct3/4, Sox2, Klf4, c-Myc） into somatic cells using iPS cell technology. However, one of the problems in these technologies is low efficiency of reprogramming. In previous studies, it was reported that the efficiency of reprogramming improved by histone deacetylase inhibitor （HDACi） treatment, but little is known of the molecular mechanism. The facilitation of histone acetylation by HDACi treatment relates to an increase in gene expression, and HDACi treatment also facilitates acetylation of non-histone proteins, and affects physiological activation. Thus, it is suggested that the acetylation of non-histone proteins relates to improvement of the reprogramming efficiency. In this review, we outline the mechanism of acetylation of non-histone proteins, and extract non-histone proteins possibly related to improving reprogramming fromGEO database.","subitem_description_type":"Abstract"}]},"item_2_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学先端技術総合研究所"}]},"item_2_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"13468693","subitem_source_identifier_type":"ISSN"}]},"item_2_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Matsubara, Keigo"},{"subitem_text_language":"en","subitem_text_value":"Kamata, Yu"},{"subitem_text_language":"en","subitem_text_value":"Magotani, Masateru"},{"subitem_text_language":"en","subitem_text_value":"&EMPTY&"},{"subitem_text_language":"en","subitem_text_value":"Yamochi, Takayuki"},{"subitem_text_language":"en","subitem_text_value":"Saeki, Kazuhiro"},{"subitem_text_language":"en","subitem_text_value":"Matsumoto, Kazuya"},{"subitem_text_language":"en","subitem_text_value":"Kishigami, Satoshi"},{"subitem_text_language":"en","subitem_text_value":"Iritani, Akira"},{"subitem_text_language":"en","subitem_text_value":"Hosoi, Yoshihiko"}]},"item_2_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学大学院生物理工学研究科"},{"subitem_text_value":"近畿大学生物理工学部　遺伝子工学科"},{"subitem_text_value":"近畿大学生物理工学部　遺伝子工学科"},{"subitem_text_value":"理化学研究所発生・再生科学総合研究センター"},{"subitem_text_value":"近畿大学大学院生物理工学研究科"},{"subitem_text_value":"近畿大学生物理工学部　遺伝子工学科"},{"subitem_text_value":"近畿大学生物理工学部　遺伝子工学科"},{"subitem_text_value":"近畿大学生物理工学部　遺伝子工学科"},{"subitem_text_value":"近畿大学生物理工学部　遺伝子工学科"},{"subitem_text_value":"近畿大学生物理工学部　遺伝子工学科"}]},"item_2_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"Graduate School of Biology-Oriented Science and Technology, Kinki University"},{"subitem_text_value":"Department of Genetic Engineering, Kinki University"},{"subitem_text_value":"Department of Genetic Engineering, Kinki University"},{"subitem_text_value":"RIKEN, Center for Developmental Biology"},{"subitem_text_value":"Graduate School of Biology-Oriented Science and Technology, Kinki University"},{"subitem_text_value":"Department of Genetic Engineering, Kinki University"},{"subitem_text_value":"Department of Genetic Engineering, Kinki University"},{"subitem_text_value":"Department of Genetic Engineering, Kinki University"},{"subitem_text_value":"Department of Genetic Engineering, Kinki University"},{"subitem_text_value":"Department of Genetic Engineering, Kinki University"}]},"item_2_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"松原,  圭吾"},{"creatorName":"マツバラ, ケイゴ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"鎌田,  悠"},{"creatorName":"カマタ, ユウ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"孫谷,  匡輝"},{"creatorName":"マゴタニ, マサテル","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Lee,  Ah,  Reum"},{"creatorName":"&EMPTY&","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"矢持,  隆之"},{"creatorName":"ヤモチ, タカユキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"佐伯,  和弘"},{"creatorName":"サエキ, カズヒロ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"松本,  和也"},{"creatorName":"マツモト, カズヤ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"岸上, 　哲士"},{"creatorName":"キシガミ, サトシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"入谷,  明"},{"creatorName":"イリタニ, アキラ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"細井, 　美彦"},{"creatorName":"ホソイ, 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