@article{oai:kindai.repo.nii.ac.jp:00009993,
 author = {松原,  圭吾 and 鎌田,  悠 and 孫谷,  匡輝 and Lee,  Ah,  Reum and 矢持,  隆之 and 佐伯,  和弘 and 松本,  和也 and 岸上, 　哲士 and 入谷,  明 and 細井, 　美彦},
 issue = {15},
 journal = {Memoirs of Institute of Advanced Technology, Kinki University, 近畿大学先端技術総合研究所紀要},
 month = {Mar},
 note = {Somatic cell nuclear transfer technology enables somatic cells to achieve totipotency. In addition, pluripotency is acquired by introduction of only four transcriptional factors（Oct3/4, Sox2, Klf4, c-Myc） into somatic cells using iPS cell technology. However, one of the problems in these technologies is low efficiency of reprogramming. In previous studies, it was reported that the efficiency of reprogramming improved by histone deacetylase inhibitor （HDACi） treatment, but little is known of the molecular mechanism. The facilitation of histone acetylation by HDACi treatment relates to an increase in gene expression, and HDACi treatment also facilitates acetylation of non-histone proteins, and affects physiological activation. Thus, it is suggested that the acetylation of non-histone proteins relates to improvement of the reprogramming efficiency. In this review, we outline the mechanism of acetylation of non-histone proteins, and extract non-histone proteins possibly related to improving reprogramming fromGEO database., application/pdf},
 pages = {1--7},
 title = {リプログラミングにおけるヒストン脱アセチル化酵素の標的タンパク質に関する考察},
 year = {2010},
 yomi = {マツバラ, ケイゴ and カマタ, ユウ and マゴタニ, マサテル and ヤモチ, タカユキ and サエキ, カズヒロ and マツモト, カズヤ and キシガミ, サトシ and イリタニ, アキラ and ホソイ, ヨシヒロ}
}