{"created":"2023-06-20T16:39:43.972927+00:00","id":9868,"links":{},"metadata":{"_buckets":{"deposit":"9f3518f8-dfe7-4ae0-9d56-4fa96fe92abd"},"_deposit":{"created_by":3,"id":"9868","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"9868"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00009868","sets":["14:923:2473:2477","21:3039:3413:3420"]},"author_link":["17902","17901","17904","17903"],"item_2_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2000-03-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"8","bibliographicPageEnd":"74","bibliographicPageStart":"67","bibliographic_titles":[{"bibliographic_title":"近畿大学農学総合研究所報告"},{"bibliographic_title":"Bulletin of the Institute for Comprehensive Agricultural Sciences, Kinki University","bibliographic_titleLang":"en"}]}]},"item_2_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"[Synopsis] Fumonisins are a series of mycotoxins produced primarily by Fusarium moniliforme, a ubiquitous contaminant of corn (maize), and F. proliferatum, a common contaminant of sorghum and rice afflicted with Fusarium sheath rot disease. Fumonisins are presumed to be tumor promoters because of the bioassay used to guide their initial isolation. Fumonisin B_1 (FB_1) has been shown to cause leukoencephalomalacia in horses, pulmonary edema in swine and cancer in rats and mice. Fumonisins are structural analogs of AAL-toxins produced by Altemaria alternata, and the putative second messenger sphingosine. Fumonisins became a food safety concern when they were demonstrated to be common contaminants of corn-derived foods and feeds. In vitro studies of mammalian cytotoxicity and phytotoxicity showed that many changes can be made in the FB_1 structure without loss of biological activity. Studies on the fate of FB_1 during food processing were initiated because of concern that FB_1 apparently destroyed during cooking of corn-derived foods may be converted to other toxic forms. During cooking radiolabeled FB_1 became covalently bound to corn proteins through side chains in a manner which may allow its release in a toxic form on digestion. Further research is needed to determine the threat to food safety posed by protein-bound mycotoxins.","subitem_description_type":"Abstract"}]},"item_2_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学農学総合研究所"}]},"item_2_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"09193022","subitem_source_identifier_type":"ISSN"}]},"item_2_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"Department of Medicinal Chemistry, College of Pharmacy, University of Minnesota"},{"subitem_text_value":"Department of Medicinal Chemistry, College of Pharmacy, University of Minnesota:Research Center for Food and Milk, Technical University of Munich"},{"subitem_text_value":"Department of Medicinal Chemistry, College of Pharmacy, University of Minnesota:Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University"},{"subitem_text_value":"Southern Weed Science Research Unit/Crop Genetics and Production Research Unit, US Dept. of Agriculture, Agricultural Research Service"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Thomas,  Shier W."}],"nameIdentifiers":[{"nameIdentifier":"17901","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Resch,  Petra"}],"nameIdentifiers":[{"nameIdentifier":"17902","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Badria,  Farid"}],"nameIdentifiers":[{"nameIdentifier":"17903","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Abbas,  Hamed K."}],"nameIdentifiers":[{"nameIdentifier":"17904","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Biological Consequences of Fumonisins","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Biological Consequences of Fumonisins"}]},"item_type_id":"2","owner":"3","path":["2477","3420"],"pubdate":{"attribute_name":"公開日","attribute_value":"2011-11-22"},"publish_date":"2011-11-22","publish_status":"0","recid":"9868","relation_version_is_last":true,"title":["Biological Consequences of Fumonisins"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-20T23:52:12.103670+00:00"}