{"created":"2023-06-20T16:39:27.651940+00:00","id":9581,"links":{},"metadata":{"_buckets":{"deposit":"6808d507-ce93-4afc-95ec-4d086eb4df1a"},"_deposit":{"created_by":3,"id":"9581","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"9581"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00009581","sets":["14:923:1149:1167","21:3039:3362:3400"]},"author_link":["17110","17111","17109","17107","17108"],"item_2_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006-09-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"42","bibliographicPageEnd":"28","bibliographicPageStart":"23","bibliographic_titles":[{"bibliographic_title":"近畿大学理工学部研究報告"},{"bibliographic_title":"Journal of the Faculty of Science and Engineering, Kinki University","bibliographic_titleLang":"en"}]}]},"item_2_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The neurotoxic acylpolyamine NPTX-594 (1) was isolated from the venom of a Madagascar Joro spider. The toxin is comprised of four constituents, i.e., 2,4-dihydroxyphenylacetic acid (Dhpa), asparagine (Asn), 4,8-diaza-1,12-dodecanediamine (Dada) and lysine (Lys). Although spider toxins are known to be strong and specific blocker against the glutamate receptors (GluRs), the interaction between the toxins and the receptors has not been clarified yet. In order to confirm visually the complex formation between spider toxins and GluRs, the syntheses of several fluorescent labeled analogs of NPTX-594 were carried out. Furthermore, the biological activities of synthetic compounds are also described.","subitem_description_type":"Abstract"}]},"item_2_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"第42回ペプチド討論会(2005年10月, 大阪）にて一部発表\n本文データの一部はCiNiiから複製したものである。","subitem_description_type":"Other"}]},"item_2_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学理工学部"}]},"item_2_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03864928","subitem_source_identifier_type":"ISSN"}]},"item_2_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Sano, Masako"},{"subitem_text_language":"en","subitem_text_value":"Nakagawa, Kana"},{"subitem_text_language":"en","subitem_text_value":"Yamaguchi, Yoshihiro"},{"subitem_text_language":"en","subitem_text_value":"Nakajima, Terumi"},{"subitem_text_language":"en","subitem_text_value":"Wakamiya, Tateaki"}]},"item_2_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学総合理工学研究科理学専攻"},{"subitem_text_value":"近畿大学理工学部理学科"},{"subitem_text_value":"近畿大学理工学部理学科"},{"subitem_text_value":"星薬科大学"},{"subitem_text_value":"近畿大学理工学部理学科"}]},"item_2_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"佐野, 雅子"},{"creatorName":"サノ, マサコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"中川, 佳奈"},{"creatorName":"ナカガワ, カナ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"山口, 仁宏"},{"creatorName":"ヤマグチ, ヨシヒロ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"中島, 暉躬"},{"creatorName":"ナカジマ, テルミ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"若宮, 建昭"},{"creatorName":"ワカミヤ, タテアキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-18"}],"displaytype":"detail","filename":"AN00064168-20060930-0023.pdf","filesize":[{"value":"1.5 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"AN00064168-20060930-0023.pdf","url":"https://kindai.repo.nii.ac.jp/record/9581/files/AN00064168-20060930-0023.pdf"},"version_id":"8385d88b-e7de-4159-ac7e-833a2722f3b7"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Fluorescent label","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Glutamate receptor","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"7-Hydroxycoumarin-3-carbonyl (HCC)","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"4-Nitrobenzo-2-oxa-1,3-diazole-7-yl (NBD)","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"NPTX-594","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Spider toxin","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"クモ毒NPTX-594の蛍光標識類縁体の合成と生物活性に関する研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"クモ毒NPTX-594の蛍光標識類縁体の合成と生物活性に関する研究"},{"subitem_title":"Study on the Syntheses and the Biological Activities of Fluorescent Labeled Analogs of Spider Toxin NPTX-594","subitem_title_language":"en"}]},"item_type_id":"2","owner":"3","path":["1167","3400"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-10-26"},"publish_date":"2010-10-26","publish_status":"0","recid":"9581","relation_version_is_last":true,"title":["クモ毒NPTX-594の蛍光標識類縁体の合成と生物活性に関する研究"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-06-20T20:24:22.139579+00:00"}