{"created":"2023-06-20T16:37:34.972317+00:00","id":7355,"links":{},"metadata":{"_buckets":{"deposit":"22c7d32f-ae1d-40e4-a045-3abd5de241c5"},"_deposit":{"created_by":3,"id":"7355","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"7355"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00007355","sets":["14:923:1711:1717","21:3039:3241:3287"]},"author_link":["12600","12604","12601","12605","12603","12602","12599","12606"],"item_2_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-12-01","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"13","bibliographicPageStart":"7","bibliographicVolumeNumber":"46","bibliographic_titles":[{"bibliographic_title":"近畿大学工学部研究報告"},{"bibliographic_title":"Research reports of the Faculty of Engineering, Kinki University","bibliographic_titleLang":"en"}]}]},"item_2_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"[SUMMARY] For ensuring useful materials including pharmaceutical compounds, it is important to extract and separate the underlying leading compounds from natural products such as plants, and to characterize their structure and pharmacological activity. Kaempferol (1), quercetin (2), quercitrin (3), rutin (4), hesperetin (5), and hesperidin (6) used in this study were flavonoids having a phenylchroman skeleton as the basic structure. Antioxidant ability, skin-whitening effect, and histamine-release suppressing effect were examined as their new physiological activities in this study. As a result, in DPPH radical scavenging effect test, which evaluates activity of antioxidant ability, high scavenging effect (90-96％) was observed in (1), (2), and (4). In skin-whitening effect test, it was clarified that (1) and (2) exert higher tyrosinase inhibition activity (42-60) than that of commercially available arbutin (7.3). In toxicity test using human alveolar epithelial cells (in vitro), meanwhile, no difference from control was observe in (3), (4), (5), and (6) at 100 μM concentration, and it was reasoned that there are no considerable toxicity.","subitem_description_type":"Abstract"}]},"item_2_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学工学部"}]},"item_2_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0386491X","subitem_source_identifier_type":"ISSN"}]},"item_2_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"Graduate School of Systems Engineering, Kinki University"},{"subitem_text_value":"Konan Chemical Industry CO.,Ltd"},{"subitem_text_value":"Kobe Koryo Co., Ltd"},{"subitem_text_value":"Department of Pharmaceutical Health Care and Life Sciences, Nihon Pharmaceutical University"},{"subitem_text_value":"Joint Research Center, Kinki University"},{"subitem_text_value":"Department of Biotechnology and Chemistry, Faculty of Engineering, Kinki University"},{"subitem_text_value":"Department of Biotechnology and Chemistry, Faculty of Engineering, Kinki University"},{"subitem_text_value":"Department of Biotechnology and Chemistry, Faculty of Engineering, Kinki University"}]},"item_2_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"近畿大学大学院システム工学研究科"},{"subitem_text_value":"甲南化工株式会社"},{"subitem_text_value":"神戸香料株式会社"},{"subitem_text_value":"日本薬科大学薬学部薬学科生命医療学分野"},{"subitem_text_value":"近畿大学共同利用センター"},{"subitem_text_value":"近畿大学工学部生物化学工学科"},{"subitem_text_value":"近畿大学工学部生物化学工学科"},{"subitem_text_value":"近畿大学工学部生物化学工学科"}]},"item_2_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Wu,  Shuhsien"},{"creatorName":"&EMPTY&","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tachibana,  Shinya"},{"creatorName":"タチバナ, シンヤ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tanimoto,  Shinichi"},{"creatorName":"タニモト, シンイチ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Inoue,  Toshio"},{"creatorName":"イノウエ, トシオ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Murai,  Yoshihira"},{"creatorName":"ムライ, ヨシヒラ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Watanabe,  Yoshiyuki"},{"creatorName":"ワタナベ, ヨシユキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Okada,  Yoshiharu"},{"creatorName":"オカダ, ヨシハル","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nomura,  Masato"},{"creatorName":"ノムラ, マサト","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-18"}],"displaytype":"detail","filename":"AN00063799-20121220-0007.pdf","filesize":[{"value":"479.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"AN00063799-20121220-0007.pdf","url":"https://kindai.repo.nii.ac.jp/record/7355/files/AN00063799-20121220-0007.pdf"},"version_id":"ae1a63b0-9982-4f70-8481-c0f02093da51"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"flavonoids","subitem_subject_scheme":"Other"},{"subitem_subject":"antioxidant","subitem_subject_scheme":"Other"},{"subitem_subject":"whitening effect","subitem_subject_scheme":"Other"},{"subitem_subject":"anti-allergic activity","subitem_subject_scheme":"Other"},{"subitem_subject":"cell toxicity","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"〈Original Papers〉Physiological Activities of Several Different Types of Flavonoids","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"〈Original Papers〉Physiological Activities of Several Different Types of Flavonoids"}]},"item_type_id":"2","owner":"3","path":["1717","3287"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-02-20"},"publish_date":"2013-02-20","publish_status":"0","recid":"7355","relation_version_is_last":true,"title":["〈Original Papers〉Physiological Activities of Several Different Types of Flavonoids"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-21T00:17:42.275183+00:00"}