{"created":"2023-06-20T16:37:33.475833+00:00","id":7331,"links":{},"metadata":{"_buckets":{"deposit":"5d5f2b1f-c1ab-4305-b5ee-c91861be9338"},"_deposit":{"created_by":3,"id":"7331","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"7331"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00007331","sets":["14:923:1711:1719","21:3039:3241:3286"]},"author_link":["12554","12556","12555","12557"],"item_2_alternative_title_3":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"〈Original Papers〉Evaluation of the toxicity of chemicals on neural cells"}]},"item_2_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-12-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"45","bibliographicPageEnd":"5","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"近畿大学工学部研究報告"},{"bibliographic_title":"Research reports of the Faculty of Engineering, Kinki University","bibliographic_titleLang":"en"}]}]},"item_2_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"[Abstract] There is an increasing interest of using bio-based polymers instead of conventional petroleum-based polymers. Biodegradable polylactic acids made from lactides are now used for the parts of cars, the drug delivery system and coatings of metal stents. The safety of the polymer was already known well. However, the toxicity of lactids is not investigated in detail. In order to evaluate the toxicity of lactides, human neuroblastoma cell lines SK-N-SH and the cultured primary neuron in rat were incubated with DL-lactide, L-lactide and toluene. While toluene was toxic, DL-lactide and L-lactide were nontoxic for both cells even high concentrations. The results indicated that lactides are safe to use.","subitem_description_type":"Abstract"}]},"item_2_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学工学部"}]},"item_2_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0386491X","subitem_source_identifier_type":"ISSN"}]},"item_2_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"OTANI, Kohei"},{"subitem_text_language":"en","subitem_text_value":"SHIRAISHI, Kohei"},{"subitem_text_language":"en","subitem_text_value":"SUGIYAMA, Kazuo"},{"subitem_text_language":"en","subitem_text_value":"YAMADA, Yasue"}]},"item_2_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学工学部生物化学工学科:近畿大学大学院システム工学研究科"},{"subitem_text_value":"近畿大学工学部生物化学工学科:近畿大学大学院システム工学研究科"},{"subitem_text_value":"近畿大学工学部生物化学工学科:近畿大学大学院システム工学研究科"},{"subitem_text_value":"近畿大学工学部生物化学工学科:近畿大学大学院システム工学研究科"}]},"item_2_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"Department of Biotechnology and Chemistry, Faculty of Engineering, Kinki University:Graduate School of Systems Engineering, Kinki University"},{"subitem_text_value":"Department of Biotechnology and Chemistry, Faculty of Engineering, Kinki University:Graduate School of Systems Engineering, Kinki University"},{"subitem_text_value":"Department of Biotechnology and Chemistry, Faculty of Engineering, Kinki University:Graduate School of Systems Engineering, Kinki University"},{"subitem_text_value":"Department of Biotechnology and Chemistry, Faculty of Engineering, Kinki University:Graduate School of Systems Engineering, Kinki University"}]},"item_2_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"大谷,  航平"},{"creatorName":"オオタニ, コウヘイ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"白石,  浩平"},{"creatorName":"シライシ, コウヘイ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"杉山,  一男"},{"creatorName":"スギヤマ, カズオ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"山田,  康枝"},{"creatorName":"ヤマダ, ヤスエ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-18"}],"displaytype":"detail","filename":"AN00063799-20111220-0001.pdf","filesize":[{"value":"666.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"AN00063799-20111220-0001.pdf","url":"https://kindai.repo.nii.ac.jp/record/7331/files/AN00063799-20111220-0001.pdf"},"version_id":"1d63171c-598a-4126-a437-32c341e58576"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"neural cells","subitem_subject_scheme":"Other"},{"subitem_subject":"human neuroblastoma","subitem_subject_scheme":"Other"},{"subitem_subject":"lactide","subitem_subject_scheme":"Other"},{"subitem_subject":"toxicity","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"〈研究論文〉神経系細胞における化学物質の毒性評価","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"〈研究論文〉神経系細胞における化学物質の毒性評価"}]},"item_type_id":"2","owner":"3","path":["1719","3286"],"pubdate":{"attribute_name":"公開日","attribute_value":"2012-03-07"},"publish_date":"2012-03-07","publish_status":"0","recid":"7331","relation_version_is_last":true,"title":["〈研究論文〉神経系細胞における化学物質の毒性評価"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-21T00:18:23.942349+00:00"}