@article{oai:kindai.repo.nii.ac.jp:00007259, author = {金安, 由里子 and 白石, 浩平 and 杉山, 一男}, issue = {43}, journal = {近畿大学工学部研究報告, Research reports of the Faculty of Engineering, Kinki University}, month = {Dec}, note = {The novel thermo-and pH-responsive interpenetrating polymer network hydrogel films (IPN: r-IPN and b-IPN) as biomedical materials were prepared from the polymerization of N-isopropylacrylamide [NiPAAm] in the presence of methylenebisacrylamide as a cross-linker and random or block copolymers composed of thermo-responsive poly(N-isopropylacrylamide)[PNiPAAm] segments and pH-responsive poly(O-meth-acrylyl-L-serine)[poly(SerMA)] segment. The random copolymer was prepared from the copolymerization of NiPAAm and SerMA precursor initiated with 2,2'-dimethylazobisisobutyrate (MAIB) as an initiator. The block copolymer was prepared from the radical polymerization of SerMA precursor initiated with the PNiPAAm azo-initiator. Two kinds of hydrogel ,r-IPN and b-IPN hydrogel,exhibited the reversible volume phase transition,swelling ⇔ shrinking,behavior in response to external stimuli such as temperature and pH., application/pdf}, pages = {13--19}, title = {<研究論文>温度とpHに応答する相互貫入型ヒドロゲル膜の作製}, year = {2009}, yomi = {カネヤマ, ユリコ and シライシ, コウヘイ and スギヤマ, カズオ} }