{"created":"2023-06-20T16:34:45.533130+00:00","id":4001,"links":{},"metadata":{"_buckets":{"deposit":"5c8d8b83-0b7a-4b85-a447-bae9b31924d3"},"_deposit":{"created_by":3,"id":"4001","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"4001"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00004001","sets":["14:2794:2798","21:2796:2799"]},"author_link":["5219"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicPageEnd":"1","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"近畿大学研究成果シーズ"},{"bibliographic_title":"Seeds Kinki University","bibliographic_titleLang":"en"}]}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"[概要]血管性認知症、アルツハイマー型認知症などは神経細胞が減少し、神経伝達物質も減少している。また、うつ病や統合失調症のような神経疾患は脳内受容体の不全が原因と考えられている。ヒトの記憶や学習に重要な働きを示し、認知症や精神疾患の発症にも関係しているNMDA 型グルタミン酸受容体に対しアンタゴニスト(拮抗作用)を与えることで認知症への効果、アゴニスト(作動作用)を与えることで神経疾患への効果が期待できる。天然に多く存在するジペプチドの中から新たにNMDA 型グルタミン酸受容体に対して生理活性のあるものを見つけ出し、医薬品として、あるいは保健機能性食品として食生活に応用することで、副作用のない穏やかな効果が期待できる。","subitem_description_type":"Abstract"}]},"item_5_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"分野：医薬・農薬, 特許出願： 特開2009-209131","subitem_description_type":"Other"}]},"item_5_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Others","subitem_description_type":"Other"}]},"item_5_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学リエゾンセンター"}]},"item_5_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学工学部生物化学工学科"}]},"item_5_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"kinki University"}]},"item_5_textarea_42":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_textarea_value":"SEEDS_kindai_B-020"}]},"item_5_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"山田,  康枝"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-18"}],"displaytype":"detail","filename":"SEEDS_kindai_B-020.pdf","filesize":[{"value":"139.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"SEEDS_kindai_B-020.pdf","url":"https://kindai.repo.nii.ac.jp/record/4001/files/SEEDS_kindai_B-020.pdf"},"version_id":"038ad757-d50a-4a6c-8dc1-282029f4dd11"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"ジペプチド","subitem_subject_scheme":"Other"},{"subitem_subject":"NMDA 型グルタミン酸受容体","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"other","resourceuri":"http://purl.org/coar/resource_type/c_1843"}]},"item_title":"医薬組成物および保健機能食品の添加物","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"医薬組成物および保健機能食品の添加物"}]},"item_type_id":"5","owner":"3","path":["2798","2799"],"pubdate":{"attribute_name":"公開日","attribute_value":"2012-10-22"},"publish_date":"2012-10-22","publish_status":"0","recid":"4001","relation_version_is_last":true,"title":["医薬組成物および保健機能食品の添加物"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-21T01:20:51.529414+00:00"}