@techreport{oai:kindai.repo.nii.ac.jp:00003493, author = {伊木, 雅之 and 佐藤, 裕保}, month = {Jan}, note = {研究成果の概要(和文): 大腿骨近位部の構造特性評価法Hip stmcture analysis (HSA)が、日本人女性で大腿骨近位部骨折リスクを表すか否かを評価した。JPOS Cohort Studyのbaseline時40歳以上で、baselineでのDXA画像からHSA指標が抽出でき、15、16年次までの骨折が問診、あるいは郵送アンケートで判明した1438人を分析した。大腿骨近位部骨折は36人確認され、年齢と推定体積骨密度を調整した最狭頸部断面係数のハザード比は1SD低下当たり1.92(95%信頼区間 1.17, 3.14)となった。HSA指標を大腿骨近位部骨折リスクの予測に利用できる可能性が示された。 研究成果の概要(英文): We evaluated whether the hip structure analysis (HSA), a geometric assessment of the proximal femur, could be used to predict hip fracture risk in subsequent 15 years in Japanese women. We analyzed 1438 women who were aged 40 years and older at the time of the JPOS baseline study, whose HSA values were extracted from their hip DXA image obtained at baseline, and whose incidence of hip fracture during the 15 years of follow-up was determined. 36 women suffered from hip fractures. The section modulus at the narrow neck of the femur was significantly associated with hip fracture risk independently of age and estimated volumetric bone density (adjusted hazard ratio: 1.92 (95% confidence interval: 1.17, 3.14)). HSA indices may be used as a risk assessment method for hip fractures., 機関番号:34419; 研究種目:挑戦的萌芽研究; 研究期間:2011~2012; 課題番号:23659362; 研究分野:医歯薬学; 科研費の分科・細目:公衆衛生学・健康科学, application/pdf}, title = {骨折リスクから見た大腿骨近位部構造解析評価値の介入開始基準の設定}, year = {2012}, yomi = {イキ, マサユキ and サトウ, ユウホ} }