{"created":"2023-06-20T16:34:16.883636+00:00","id":3432,"links":{},"metadata":{"_buckets":{"deposit":"9164b2f4-c949-40ea-afd0-ef95362fc2ac"},"_deposit":{"created_by":3,"id":"3432","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3432"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00003432","sets":["14:2667:2668:2987","21:2669:2670:2988"]},"author_link":["4056","4055","4054"],"item_8_alternative_title_3":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Development of an interface to refer OMICS information into clinic"}]},"item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-01-01","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"6","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費助成事業研究成果報告書 (2014. )"}]}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文): メインコンピューター上に仮想カルテを作成し, ファイルメーカーを用いて, 患者ごとの参照画面を作成した. 参照画面には年齢, 病期, 組織型といった臨床情報とともに, 後述する, 数値化されたマイクロアレイ情報が表示されるようにした. また, 各患者のマイクロアレイ情報に基づく癌の生物学的なプロフィールも図示できるようにした. 学内施設において卵巣癌症例の手術標本のマイクロアレイ解析をおこない, 粗データをメインコンピューターに蓄積した. 各細胞内シグナルの活性度を表すと考えられる遺伝子群をsignatureとして抽出し, ssGSEAを用いて, おのおののsignatureの強さを0-1の間に数値化した.            研究成果の概要（英文): Virtial chart for this study was created in the main computer to stock patient information safely. All the clinical and bioinformatics data except for personal identification were stored. Ovarian cancer specimen was subjected to the analysis of microarray in inhouse facility and all the data was stored in the main computer. Then, intracellular signals of each sample was calculated and　refined into 1 to 10 scores, so that enables to estimate what kind of intracellular signal was activated in individual patient. These analysis was performed in a routine manner.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目：挑戦的萌芽研究;  研究期間：2013～2014;   課題番号：25670703;   研究分野：婦人科腫瘍学;   科研費の分科・細目：","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_relation_11":{"attribute_name":"著者 外部リンク","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/d/r/80283597.ja.html"}]},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/d/r/00162694.ja.html"}]},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/d/r/50301106.ja.html"}]}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"},{"subitem_text_value":"研究分担者"},{"subitem_text_value":"研究分担者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"MANDAI, Masaki"},{"subitem_text_language":"en","subitem_text_value":"SHIMIZU, Akira"},{"subitem_text_language":"en","subitem_text_value":"YAMADA, Ryo"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学医学部; 教授"},{"subitem_text_value":"京都大学医学部; 教授"},{"subitem_text_value":"京都大学医学部; 教授"}]},"item_8_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"Kinki University"},{"subitem_text_value":"Kyoto University"},{"subitem_text_value":"Kyoto University"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"万代,  昌紀"},{"creatorName":"マンダイ, マサキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"清水,  章"},{"creatorName":"シミズ, アキラ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"山田,  亮"},{"creatorName":"ヤマダ, リョウ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-17"}],"displaytype":"detail","filename":"KAKEN_25670703seika.pdf","filesize":[{"value":"327.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KAKEN_25670703seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/3432/files/KAKEN_25670703seika.pdf"},"version_id":"9065f595-5128-4fb2-883f-d10d9b3db764"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"卵巣癌","subitem_subject_scheme":"Other"},{"subitem_subject":"マイクロアレイ","subitem_subject_scheme":"Other"},{"subitem_subject":"細胞内シグナル","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"OMICS情報を臨床診療に反映するためのインターフェースとバーチャルカルテの開発","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"OMICS情報を臨床診療に反映するためのインターフェースとバーチャルカルテの開発"}]},"item_type_id":"8","owner":"3","path":["2987","2988"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-10-23"},"publish_date":"2015-10-23","publish_status":"0","recid":"3432","relation_version_is_last":true,"title":["OMICS情報を臨床診療に反映するためのインターフェースとバーチャルカルテの開発"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-21T01:35:47.477611+00:00"}