@techreport{oai:kindai.repo.nii.ac.jp:00003422,
 author = {伊木,  雅之 and 車谷,  典男 and 玉置,  淳子 and 藤田,  裕規 and 佐藤,  裕保},
 month = {Jan},
 note = {研究成果の概要（和文): 藤原京スタディ男性骨粗鬆症研究参加者を5年追跡して新規骨折を把握し, 骨折リスク評価モデルFRAXの有用性を確認し, 骨折と死亡, 心血管疾患との関連を検討した. 主要骨粗鬆症性骨折(MOF)をFRAXの予測確率で予測した場合のROC曲線下面積は0.681だった. 新規骨折は死亡のリスクをfrailty indicesを調整しても2.75倍に上げた. MOFを起こすとdefinite anginaのリスクが2.9倍になった. 日本人男性においてもFRAXはある程度の骨折予測性能を持つが, 改良の余地があった. 骨折は死亡のリスクを上げ, その一部は虚血性心疾患である可能性が示唆された.           研究成果の概要（英文): Among 1999 male participants who completed 5-year follow-up in the Fujiwara-kyo Osteoporosis Risk in Men Study, we identify 111 fractures in 99 men including 23 major osteoporotic fractures (MOF) in 22 men, 138 deaths and 66 definite angina according to Rose Angina Questionnaire. The risk of MOF was calculated using clinical risk factors at baseline by FRAX. The area under the receiver operating characteristics curve for MOF predicted by FRAX was 0.681 which was greater than that reported for the original cohorts where FRAX was developed. Incident fracture 2.75 times increased the risk of death even after adjustment for frailty indices. Participants with incident MOF showed insignificant but 2.9 times increased risk of angina compared to those without. FRAX predicts the risk of MOF in Japanese men but its validity should be improved. Fracture appeared to increase the risk of death possibly and partly through increase in risk of coronary heart diseases., 研究種目：基盤研究(B);  研究期間：2012～2014;   課題番号：24390170;   研究分野：医歯薬学;   科研費の分科・細目：, application/pdf},
 title = {骨折リスク評価を基盤に関連疾患の同時対策を目指す男性骨粗鬆症コホート5年次追跡},
 year = {2014},
 yomi = {イキ, マサユキ and クルマタニ, ノリオ and タマキ, ジュンコ and フジタ, ユウキ and サトウ, ユウホ}
}