{"created":"2023-06-20T16:34:16.299268+00:00","id":3419,"links":{},"metadata":{"_buckets":{"deposit":"34fe7c4a-f519-4abb-89f9-cf79a676690d"},"_deposit":{"created_by":3,"id":"3419","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3419"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00003419","sets":["14:2667:2668:2987","21:2669:2670:2988"]},"author_link":["4014","4013","4012","4011"],"item_8_alternative_title_3":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"The strategy for elucidation of diabetogenic factors:functional partition and reintegrate"}]},"item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-01-01","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"6","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費助成事業研究成果報告書 (2014 )"}]}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文): 2型糖尿病は, 複数の遺伝子により構成される遺伝因子と, 環境因子の複雑な相互作用により発症する多因子疾患であり, ヒトを用いた解析では感受性遺伝子同定は困難である. 本研究では, 糖尿病モデルマウスおよび交配実験において得られたコンソミック・コンジェニック系統を用いて, 2型糖尿病の疾患感受性遺伝子領域を同定し, その作用機序を解明した.                      研究成果の概要（英文): Type 2 diabetes are multifactorial diseases caused by a complex interaction  of environmental and genetic factors, with the latter consisting of multiple susceptibility genes, making it difficult to clarify their functions and interactions in conferring susceptibility to type 2 diabetes in humans. In this study, we constructed consomic and congenic strains, in which the NSY-derived diabetogenic region was introgressed onto the genetic background of control mice. We succeeded to localize and characterize the function of diabetogenic region in the NSY.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目：基盤研究(C);  研究期間：2012～2014;   課題番号：24591346;   研究分野：糖尿病;   科研費の分科・細目：","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_relation_11":{"attribute_name":"著者 外部リンク","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/d/r/10449837.ja.html"}]},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/d/r/20221062.ja.html"}]},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/d/r/80423185.ja.html"}]},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/d/r/90460849.ja.html"}]}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"},{"subitem_text_value":"研究分担者"},{"subitem_text_value":"研究分担者"},{"subitem_text_value":"研究分担者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"BABAYA, Naru"},{"subitem_text_language":"en","subitem_text_value":"IKEGAMI, Hiroshi"},{"subitem_text_language":"en","subitem_text_value":"KAWABATA, Yumiko"},{"subitem_text_language":"en","subitem_text_value":"NOSO, Shinsuke"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学医学部; 講師"},{"subitem_text_value":"近畿大学医学部; 教授"},{"subitem_text_value":"近畿大学医学部; 准教授"},{"subitem_text_value":"近畿大学医学部; 講師"}]},"item_8_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"Kinki University"},{"subitem_text_value":"Kinki University"},{"subitem_text_value":"Kinki University"},{"subitem_text_value":"Kinki University"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"馬場谷,  成"},{"creatorName":"ババヤ, ナル","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"池上,  博司"},{"creatorName":"イケガミ, ヒロシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"川畑,  由美子"},{"creatorName":"カワバタ, ユミコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"能宗,  伸輔"},{"creatorName":"ノウソウ, シンスケ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-17"}],"displaytype":"detail","filename":"24591346seika.pdf","filesize":[{"value":"266.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"24591346seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/3419/files/24591346seika.pdf"},"version_id":"7cb5aedb-43ec-4e86-a2b1-61da5b975722"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"糖尿病疾患感受性遺伝子","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"2型糖尿病発症因子解明のための戦略 : 機能分割と再統合","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"2型糖尿病発症因子解明のための戦略 : 機能分割と再統合"}]},"item_type_id":"8","owner":"3","path":["2987","2988"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-10-09"},"publish_date":"2015-10-09","publish_status":"0","recid":"3419","relation_version_is_last":true,"title":["2型糖尿病発症因子解明のための戦略 : 機能分割と再統合"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-21T01:36:16.536638+00:00"}