{"created":"2023-06-20T16:34:08.958191+00:00","id":3247,"links":{},"metadata":{"_buckets":{"deposit":"b6d27546-8f15-4e1b-87ef-47e0f66db572"},"_deposit":{"created_by":3,"id":"3247","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3247"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00003247","sets":["14:2667:2685:2686","21:2669:2687:2688"]},"author_link":["3726","3721","3719","3724","3722","3717","3725","3718","3720","3723"],"item_8_alternative_title_3":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Association of perioperative changes in plasma and salivary substance P with cough reflex sensitivity and postoperative aspiration after esophagectomy"}]},"item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-01-01","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"4","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費補助金研究成果報告書 (2011. )"}]}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：高齢者の誤嚥は、咳および嚥下反射を制御するサブスタンスP（SP）の分泌低下が原因である。そこで、高齢者に多く、術後に誤嚥のリスクの高い食道癌手術患者における術前後の血中SP 値の推移を調べ、誤嚥発症との関連を検討した。術前後で有意な変動は見られなかったが、術前より低値を示す症例は有意に誤嚥を発症する率が高く（p＝0.004）、術前血中SP 低値（60pg/ml 以下）の症例は術後誤嚥発症のハイリスク群と考えられた。                 研究成果の概要（英文）：Aspiration of elderly patients is caused by decreased secretion of substance P (SP) that regulates cough and swallowing reflexes. We prospectively investigated the change of perioperative plasma SP concentration in patients with esophageal cancer undergoing esophagectomy and examined the association with development of aspiration. The plasma SP concentration did not show a significant change in the perioperative period. However, decreased preoperative SP concentration had a strong association with postoperative aspiration (p=0.004), suggesting that patients with decreased preoperative plasma SP concentration (60 pg/ml or less) might carry a higher risk of development of postoperative aspiration in patients after esophagectomy.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目：基盤研究（C);  研究期間：2009～2011;   課題番号：21591716;   研究分野：医歯薬学;   科研費の分科・細目：外科系臨床医学・消化器外科学","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_relation_11":{"attribute_name":"著者 外部リンク","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"http://kaken.nii.ac.jp/d/r/10324782.ja.html"}]},{"subitem_relation_name":[{"subitem_relation_name_text":"http://kaken.nii.ac.jp/d/r/70144475.ja.html"}]},{"subitem_relation_name":[{"subitem_relation_name_text":"http://kaken.nii.ac.jp/d/r/80351609.ja.html"}]},{"subitem_relation_name":[{"subitem_relation_name_text":"http://kaken.nii.ac.jp/d/r/00278681.ja.html"}]},{"subitem_relation_name":[{"subitem_relation_name_text":"http://kaken.nii.ac.jp/d/r/80340793.ja.html"}]},{"subitem_relation_name":[{"subitem_relation_name_text":"http://kaken.nii.ac.jp/d/r/20411605.ja.html"}]}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"},{"subitem_text_value":"研究分担者"},{"subitem_text_value":"研究分担者"},{"subitem_text_value":"研究分担者"},{"subitem_text_value":"研究分担者"},{"subitem_text_value":"研究分担者"},{"subitem_text_value":"研究分担者"},{"subitem_text_value":"研究分担者"},{"subitem_text_value":"研究分担者"},{"subitem_text_value":"研究分担者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"YASUDA, TAKUSHI"},{"subitem_text_language":"en","subitem_text_value":"SHIOZAKI, HITOSHI"},{"subitem_text_language":"en","subitem_text_value":"IMAMOTO, HARUHIKO"},{"subitem_text_language":"en","subitem_text_value":"IMANO, MOTOHIRO"},{"subitem_text_language":"en","subitem_text_value":"SHINKAI, MASAYUKI"},{"subitem_text_language":"en","subitem_text_value":"YING, FENG-PENG"},{"subitem_text_language":"en","subitem_text_value":"YASUDA, ATSUSHI"},{"subitem_text_language":"en","subitem_text_value":"SHIRAISHI, OSAMU"},{"subitem_text_language":"en","subitem_text_value":"NISHIKI, KOHEI"},{"subitem_text_language":"en","subitem_text_value":"KATO, HIROAKI"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学医学部; 准教授"},{"subitem_text_value":"近畿大学; 学長"},{"subitem_text_value":"近畿大学医学部; 教授"},{"subitem_text_value":"近畿大学医学部; 准教授"},{"subitem_text_value":"近畿大学医学部; 講師"},{"subitem_text_value":"近畿大学医学部; 非常勤講師"},{"subitem_text_value":"近畿大学医学部; 講師"},{"subitem_text_value":"近畿大学医学部附属病院; 講師"},{"subitem_text_value":"近畿大学医学部附属病院; 助教"},{"subitem_text_value":"近畿大学医学部附属病院; 助教"}]},"item_8_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"Kinki University"},{"subitem_text_value":"Kinki University"},{"subitem_text_value":"Kinki University"},{"subitem_text_value":"Kinki University"},{"subitem_text_value":"Kinki University"},{"subitem_text_value":"Kinki University"},{"subitem_text_value":"Kinki University"},{"subitem_text_value":"Kinki University"},{"subitem_text_value":"Kinki University"},{"subitem_text_value":"Kinki University"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"安田,  卓司"},{"creatorName":"ヤスダ, タクシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"塩﨑,  均"},{"creatorName":"シオザキ, ヒトシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"今本,  治彦"},{"creatorName":"イマモト, ハルヒコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"今野,  元博"},{"creatorName":"イマノ, モトヒロ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"新海,  政幸"},{"creatorName":"シンカイ, マサユキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"彭,  英峰"},{"creatorName":"&EMPTY&","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"安田,  篤"},{"creatorName":"ヤスダ, アツシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"白石,  治"},{"creatorName":"シライシ, オサム","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"錦,  耕平"},{"creatorName":"ニシキ, コウヘイ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"加藤,  寛章"},{"creatorName":"カトウ, ヒロアキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-17"}],"displaytype":"detail","filename":"KAKEN_21591716seika.pdf","filesize":[{"value":"160.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KAKEN_21591716seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/3247/files/KAKEN_21591716seika.pdf"},"version_id":"b0c496d0-2d9e-44c9-961e-24024711e41d"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"サブスタンスP","subitem_subject_scheme":"Other"},{"subitem_subject":"誤嚥","subitem_subject_scheme":"Other"},{"subitem_subject":"食道切除術","subitem_subject_scheme":"Other"},{"subitem_subject":"咳嗽反射","subitem_subject_scheme":"Other"},{"subitem_subject":"嚥下機能","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"サブスタンスPの分泌制御による食道癌術後の誤嚥性肺炎の予防と嚥下機能改善","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"サブスタンスPの分泌制御による食道癌術後の誤嚥性肺炎の予防と嚥下機能改善"}]},"item_type_id":"8","owner":"3","path":["2686","2688"],"pubdate":{"attribute_name":"公開日","attribute_value":"2012-11-13"},"publish_date":"2012-11-13","publish_status":"0","recid":"3247","relation_version_is_last":true,"title":["サブスタンスPの分泌制御による食道癌術後の誤嚥性肺炎の予防と嚥下機能改善"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-21T01:41:55.371116+00:00"}