{"created":"2023-06-20T16:34:07.176114+00:00","id":3205,"links":{},"metadata":{"_buckets":{"deposit":"8097f519-f256-4d3e-a9b2-843351cbde97"},"_deposit":{"created_by":3,"id":"3205","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3205"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00003205","sets":["14:2667:2685:2686","21:2669:2687:2688"]},"author_link":["3646","3644","3645"],"item_8_alternative_title_3":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Development of artificial articular cartilage with a region selective osteoconduction using a nanotechnology"}]},"item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-01-01","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"5","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費補助金研究成果報告書 (2011. )"}]}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：関節軟骨の病変部だけを人工軟骨に置換するための材料開発とそれを骨組織に永続的に固定する方法を研究した。人工軟骨であるポリビニールゲルが生体軟骨と摩擦する面は生体不活性、骨との接触面は強く接着できる部位選択組織融合型接着方法を研究した。接着層としてハイドロキシアパタイト積層超薄膜（厚さ350 nm）を利用することとし、ゲルとアパタイト薄膜の生体適合性ならびに材料学的・力学的特性の向上方法を検索した。　　　　　　　　研究成果の概要（英文）：We studied on a partial repalcementable artificial articular cartilage, composed of polyvinyl alcohol hydrogel (PVA-H), or a composite osteo-chondral device (COD). The COD is able to replace the local lesion of natural articular cartilage. A long-term fixation technique between the COD and osseous tissues was studied. The COD surface must have bio-inert function. On the other hand, in the boundary between the COD and living bone, the osteoconductive adhesion is necessary. That is, the partial selective adhesion function (PSAF) was investigated. We have materialized PSAF in the COD by integration the PVA-H and several kinds of apatite thin film. Biocompatibility, mechanical strength and material property of both PVA-Hs and the thin films were studied.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目：基盤研究（C）;  研究期間：2009～ 2011;   課題番号：21500435;   研究分野：総合領域;   科研費の分科・細目：人間医工学、医用生体工学・生体材料学","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_relation_11":{"attribute_name":"著者 外部リンク","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/d/r/20173057.ja.html"}]},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/d/r/20282238.ja.html"}]},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/d/r/00432328.ja.html"}]}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"},{"subitem_text_value":"研究分担者"},{"subitem_text_value":"連携研究者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"HAYAMI, TAKASHI"},{"subitem_text_language":"en","subitem_text_value":"KUSUNOKI, MASANOBU"},{"subitem_text_language":"en","subitem_text_value":"MASTUMURA, KAZUAKI"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学生物理工学部; 教授"},{"subitem_text_value":"近畿大学生物理工学部; 教授"},{"subitem_text_value":"北陸先端科学技術大学院大学マテリアルサイエンス研究科; 准教授"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"速水,  尚"},{"creatorName":"ハヤミ, タカシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"楠,  正暢"},{"creatorName":"クスノキ, マサノブ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"松村,  和明"},{"creatorName":"マツムラ, カズアキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-17"}],"displaytype":"detail","filename":"KAKEN_21500435seika.pdf","filesize":[{"value":"546.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KAKEN_21500435seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/3205/files/KAKEN_21500435seika.pdf"},"version_id":"317108ef-340c-4b40-8464-0c0db82c8522"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"生体機能材料","subitem_subject_scheme":"Other"},{"subitem_subject":"人工関節軟骨","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"ナノテクノロジーを利用した部位選択的骨伝導能を有する人工関節軟骨の開発","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ナノテクノロジーを利用した部位選択的骨伝導能を有する人工関節軟骨の開発"}]},"item_type_id":"8","owner":"3","path":["2686","2688"],"pubdate":{"attribute_name":"公開日","attribute_value":"2012-10-01"},"publish_date":"2012-10-01","publish_status":"0","recid":"3205","relation_version_is_last":true,"title":["ナノテクノロジーを利用した部位選択的骨伝導能を有する人工関節軟骨の開発"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-21T01:43:11.891145+00:00"}