{"created":"2023-06-20T16:34:04.435505+00:00","id":3157,"links":{},"metadata":{"_buckets":{"deposit":"84007729-6dce-424e-b18e-e5df49e1e898"},"_deposit":{"created_by":3,"id":"3157","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3157"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00003157","sets":["14:2667:2689:2693","21:2669:2691:2694"]},"author_link":["3520","3519"],"item_8_alternative_title_3":{"attribute_name":"その他(別言語等)のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"The gender difference in the mechanisms that control glomerular hemodynamics."}]},"item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-01-01","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"4","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費補助金研究成果報告書 (2010. )"}]}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要(和文): 腎疾患の病態・進展に重要な糸球体血行動態調節機構に性差が存在するか否かを検討したが、糸球体血行動態の主な調節因子である輸出入細動脈の血管反応性・血管内皮機能に有意な性差を認める事はなかった。各種性ホルモンの有意な血管作用も認められず、生理的・病態生理的な成果は得られなかった。 本研究では、腎濾過機能の調節に重要な髄質血流の性差を検討する実験系や腎細動脈の血管平滑筋細胞と内皮細胞の培養系確立を目指した実験系に関して、若干ながら進行が得られた。 研究成果の概要(英文): We found neither gender difference in the control mechanisms of glomerular hemodynamics nor in the vascular reactivity of renal arterioles. In addition, at least under our experimental conditions any sexual hormone did not exert significant vascular actions on renal arterioles. In the present study, we could not establish but somewhat develop an experimental system to study the possible gender differences in renal medullary blood flow. We also tried to develop a culture system of vascular smooth muscle cells and endothelial cells of renal arterioles to study the detail cellular mechanisms underlying the physiological and/or pathophysiological glomerular hemodynamics.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目:基盤研究(C); 研究期間:2008~2010; 課題番号:20590968; 研究分野:医歯薬学; 科研費の分科・細目:腎臓内科学","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_relation_11":{"attribute_name":"著者 外部リンク","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/r/60323010"}]},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/r/70441079"}]}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"},{"subitem_text_value":"研究分担者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"ARIMA, SHUJI"},{"subitem_text_language":"en","subitem_text_value":"TANIYAMA, YOSHIHIRO"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学医学部; 准教授"},{"subitem_text_value":"近畿大学医学部; 講師"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"有馬, 秀二"},{"creatorName":"アリマ, シュウジ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"谷山, 佳弘"},{"creatorName":"タニヤマ, ヨシヒロ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-17"}],"displaytype":"detail","filename":"KAKEN_20590968seika.pdf","filesize":[{"value":"323.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KAKEN_20590968seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/3157/files/KAKEN_20590968seika.pdf"},"version_id":"d06fe1e0-4cda-40d2-86a2-18227efb156f"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"輸出入細動脈","subitem_subject_scheme":"Other"},{"subitem_subject":"性差","subitem_subject_scheme":"Other"},{"subitem_subject":"血管内皮機能","subitem_subject_scheme":"Other"},{"subitem_subject":"性ホルモン","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"腎糸球体血行動態調節機構の性差:腎臓の老化機序を含めた生理的・病態生理的意義","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"腎糸球体血行動態調節機構の性差:腎臓の老化機序を含めた生理的・病態生理的意義"}]},"item_type_id":"8","owner":"3","path":["2693","2694"],"pubdate":{"attribute_name":"公開日","attribute_value":"2011-07-08"},"publish_date":"2011-07-08","publish_status":"0","recid":"3157","relation_version_is_last":true,"title":["腎糸球体血行動態調節機構の性差:腎臓の老化機序を含めた生理的・病態生理的意義"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-21T01:44:49.547432+00:00"}