{"created":"2023-06-20T16:34:02.151538+00:00","id":3116,"links":{},"metadata":{"_buckets":{"deposit":"3608013e-243f-4f9b-acc8-fdf87b1bb365"},"_deposit":{"created_by":3,"id":"3116","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3116"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00003116","sets":["14:2667:2689:2693","21:2669:2691:2694"]},"author_link":["3421","3419","3420","3418"],"item_8_alternative_title_3":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Implant treatment in next generation by preparation technology of nano apatite thin film"}]},"item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-01-01","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"6","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費補助金研究成果報告書 (2010. )"}]}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）： レーザーアブレーション法によるハイドロキシアパタイト(HAp)と生体アパタイト(BAp)の薄膜化および積層化技術と、シート化技術を用いて、治療部位に整合した生体活性を有する骨誘導再生用BApメンブレン(BApGBR)と生体内安定性と生体活性を併せ持つ複合機能2層（BAp/HAp）インプラントを作製した。薄膜および積層膜の評価は化学的、物理的、分子生物学的特性について行った。また、BApGBRメンブレンと新規複合機能インプラントの臨床模擬試験を、イヌ下顎歯槽骨および大腿骨欠損モデル埋入試験を用い、次世代インプラント治療としての有用性を確認した。    研究成果の概要（英文）： In this study, we have aimed to develop following two types of medical/dental devices that are effective for the implant treatment in next generation. One is the freestanding membrane of biological apatite (BAp) that can be applied to the guided bone regeneration (GBR) method with the suitable bioactivity for affected region. The other is the implant in that two functions of biostability and biocompatibility were harmonized by the bilayered structure of BAp/hydroxyapatite (HAp). Both devices were prepared by using a pulsed laser deposition (PLD) technique for a thin film and bilayer formation technology. The prepared thin films and the bilayer were evaluated on chemical, physical and molecular biology. Clinical simulation test of BApGBR membrane and the function harmonized implant was carried out by using the mandibular alveolar bone and the femoral defect model of dog. As the results, the usefulness of our devices was confirmed as an implant treatment in next generation.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目：基盤研究（B）;  研究期間：2008～2010;   課題番号：20390503;   研究分野：医歯薬学;   科研費の分科・細目：歯学・歯科医用工学・再生歯学","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_relation_11":{"attribute_name":"著者 外部リンク","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/r/40157102"}]},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/r/20228430"}]},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/r/10181083"}]},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/r/20282238"}]}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"},{"subitem_text_value":"研究分担者"},{"subitem_text_value":"研究分担者"},{"subitem_text_value":"研究分担者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"HONTSU, SHIGEKI"},{"subitem_text_language":"en","subitem_text_value":"HASHIMOTO, YOSHIYA"},{"subitem_text_language":"en","subitem_text_value":"HIGUCHI, YUICHI"},{"subitem_text_language":"en","subitem_text_value":"KUSUNOKI, MASANOBU"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学生物理工学部; 教授"},{"subitem_text_value":"大阪歯科大学歯学部; 助教"},{"subitem_text_value":"大阪歯科大学歯学部; 講師"},{"subitem_text_value":"近畿大学生物理工学部; 准教授"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"本津,  茂樹"},{"creatorName":"ホンツ, シゲキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"3418","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"20282238","nameIdentifierScheme":"研究者番号","nameIdentifierURI":" "}]},{"creatorNames":[{"creatorName":"橋本,  典也"},{"creatorName":"ハシモト, ヨシヤ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"3419","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"樋口,  裕一"},{"creatorName":"ヒグチ, ユウイチ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"3420","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"楠,  正暢"},{"creatorName":"クスノキ, マサノブ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"3421","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-17"}],"displaytype":"detail","filename":"KAKEN_20390503seika.pdf","filesize":[{"value":"483.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KAKEN_20390503seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/3116/files/KAKEN_20390503seika.pdf"},"version_id":"0273192a-4096-417e-914f-e49551c29b46"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"インプラント","subitem_subject_scheme":"Other"},{"subitem_subject":"アパタイト","subitem_subject_scheme":"Other"},{"subitem_subject":"メンブレン","subitem_subject_scheme":"Other"},{"subitem_subject":"骨誘導再生","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"ナノアパタイト薄膜作製技術を用いた次世代インプラント治療","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ナノアパタイト薄膜作製技術を用いた次世代インプラント治療"}]},"item_type_id":"8","owner":"3","path":["2693","2694"],"pubdate":{"attribute_name":"公開日","attribute_value":"2011-07-08"},"publish_date":"2011-07-08","publish_status":"0","recid":"3116","relation_version_is_last":true,"title":["ナノアパタイト薄膜作製技術を用いた次世代インプラント治療"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-21T01:46:10.748321+00:00"}