{"created":"2023-06-20T16:34:01.264600+00:00","id":3099,"links":{},"metadata":{"_buckets":{"deposit":"ce4cdb31-2d9a-4739-b5df-a8ba71b9633b"},"_deposit":{"created_by":3,"id":"3099","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3099"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00003099","sets":["14:2667:2689:2690","21:2669:2691:2692"]},"author_link":["3386"],"item_8_alternative_title_3":{"attribute_name":"その他(別言語等)のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"An examination of entrainment mechanisms of the peripheral clock"}]},"item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-01-01","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"4","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費補助金研究成果報告書 (2010. )"}]}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要(和文): 末梢時計の位相制御におけるグルココルチコイドと摂食時刻の関与を調べるために、副腎除去ラットを用いて給餌時刻の制限とグルココルチコイドの投与を行い、肝臓、腎臓、肺の時計遺伝子発現に与える影響を調べた。その結果から、グルココルチコイドの日内変動が腎臓、肺の末梢時計の位相調節に関与することが示唆された。また、肝臓の末梢時計は摂食時刻により強い影響を受けることが明らかとなり、臓器による同調因子の影響力の違いが示された。 研究成果の概要(英文):To elucidate the entrainment mechanisms of the peripheral clock, we carried out a series of experiments using the glucocorticoid injection and restricted feeding with a relationship of a reverse phase mutually. The results indicated the differences of the dominant timing factor among kinds of organs. The peripheral clock of the kidney and lung entrained to the time of corticosterone administration. In contrast, the liver clock was synchronized to the time of feeding.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目:若手研究(B); 研究期間:2009~2010; 課題番号:21790230; 研究分野:医歯薬学; 科研費の分科・細目:基礎医学・環境生理学(含体力医学・栄養生理学)","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_relation_11":{"attribute_name":"著者 外部リンク","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/r/30460843"}]}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"SUJINO, MITSUGU"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学医学部; 助教"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"筋野, 貢"},{"creatorName":"スジノ, ミツグ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-17"}],"displaytype":"detail","filename":"KAKEN_21790230seika.pdf","filesize":[{"value":"519.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KAKEN_21790230seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/3099/files/KAKEN_21790230seika.pdf"},"version_id":"c691e2fa-7d53-4358-b2f0-b7b3d71ffd66"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"生物時計","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"末梢時計の制御機構の解明および末梢時計操作の試み","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"末梢時計の制御機構の解明および末梢時計操作の試み"}]},"item_type_id":"8","owner":"3","path":["2690","2692"],"pubdate":{"attribute_name":"公開日","attribute_value":"2011-06-28"},"publish_date":"2011-06-28","publish_status":"0","recid":"3099","relation_version_is_last":true,"title":["末梢時計の制御機構の解明および末梢時計操作の試み"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-21T01:46:42.172270+00:00"}