{"created":"2023-06-20T16:34:00.923163+00:00","id":3092,"links":{},"metadata":{"_buckets":{"deposit":"f25bd258-74b5-4246-82c4-d1169fe5808d"},"_deposit":{"created_by":3,"id":"3092","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3092"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00003092","sets":["14:2667:2689:2690","21:2669:2691:2692"]},"author_link":["3381"],"item_8_alternative_title_3":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Estimation of the absorption and metabolic mechanism of monoacylglycerols in the small intestine"}]},"item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-01-01","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"4","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費補助金研究成果報告書 (2010. )"}]}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）： 食事性脂質の消化産物の小腸細胞における動態を明らかにするため、細胞質輸送体の一つである脂肪酸結合タンパク質に対するモノアシルグリセロール（MG）および脂肪酸の結合を評価した。その結果脂肪酸の炭素鎖長が重要であることが確認されたが、MG については競合性が弱く結合性の特徴は明確でなかった。加えて、脂肪酸輸送担体の一つであるCD36 を発現させた小腸モデル培養細胞株を樹立し、実験動物においては異なる脂質を投与したときのリンパ液における脂質構成を評価することが可能となった。     研究成果の概要（英文）：In this study, in vitro binding assay, cell culture study, and in vivo rat study were performed. In in vitro study, the binding abilities of monoacylglycerols (MGs) and free fatty acids to intestinal fatty-acid binding proteins (FABPs) were examined. The result has indicated that the carbon chain length of free fatty acids is a key factor to determine the binding ability, whereas MGs’ binding was not clear. In the cell culture study, the stable Caco-2 cell line expressing CD36 membrane protein was established. Furthermore, the lymphatic transport of various dietary lipids was estimated using thoracic-lymph cannulated rats.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目：若手研究（B）;   研究期間：2009 年度～2010 年度;   課題番号：21780127;    研究分野：農学;    科研費の分科・細目：食品科学","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_relation_11":{"attribute_name":"著者 外部リンク","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/r/40294681"}]}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"MUROTA, KAEKO"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学理工学部; 講師"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"室田,  佳恵子"},{"creatorName":"ムロタ, カエコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"3381","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"40294681","nameIdentifierScheme":"研究者番号","nameIdentifierURI":" "}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-17"}],"displaytype":"detail","filename":"KAKEN_21780127seika.pdf","filesize":[{"value":"223.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KAKEN_21780127seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/3092/files/KAKEN_21780127seika.pdf"},"version_id":"55d88a7d-49ee-4d48-abe4-93ad3ddeec77"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"モノアシルグリセロールの腸管における吸収代謝動態の解明","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"モノアシルグリセロールの腸管における吸収代謝動態の解明"}]},"item_type_id":"8","owner":"3","path":["2690","2692"],"pubdate":{"attribute_name":"公開日","attribute_value":"2011-06-28"},"publish_date":"2011-06-28","publish_status":"0","recid":"3092","relation_version_is_last":true,"title":["モノアシルグリセロールの腸管における吸収代謝動態の解明"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-21T01:46:56.443326+00:00"}