{"created":"2023-06-20T16:34:00.244067+00:00","id":3076,"links":{},"metadata":{"_buckets":{"deposit":"766656af-f4d9-4878-90f3-e333537a9a3f"},"_deposit":{"created_by":3,"id":"3076","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3076"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00003076","sets":["14:2667:2695:2699","21:2669:2697:2700"]},"author_link":["3363"],"item_8_alternative_title_3":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"The effect of nutritional management during fetal life on vascular function and oxidative stress in rats with adult-onset diseases"}]},"item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-01-01","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"4","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費補助金研究成果報告書 (2009. )"}]}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"胎生期の低栄養曝露により、出生後に生活習慣病・血管障害の罹患率が上昇することが報告されている。さらに、高血圧・脳卒中の遺伝モデルラットSHRSPを用いた以前の研究において、妊娠中の母獣にタンパク制限を行うと食塩感受性が亢進することを確認している。本研究ではこの動物モデルを用いて、胎生期の低タンパク曝露が血管機能に及ぼす影響について検討した。その結果、代謝異常をともなうSHRSPでは、胎生期の栄養環境は血圧の上昇とは独立して血管機能に影響している可能性が示唆された。（英文） Some research show that the increase in the prevalence of adult-onset diseases and vascular disorders after the birth by exposure to undernutrition during fetal life. Moreover, previous research using stroke-prone spontaneously hypertensive rats (SHRSP), an animal model which develops hypertension and stroke, demonstrated the increased salt-sensitivity in rats whose dams were fed protein restricted diets during pregnancy. In this study, the effect of maternal exposure to low-protein diet on postnatal vascular function was examined. As a result, the study revealed that nutritional environment during fetal life possibly affects vascular function independently of increased blood pressure in SHRSP with metabolic disorders.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目：若手研究(スタートアップ)研究期間：2008～2009課題番号：20880030研究分野：農学科研費の分科・細目：農芸化学・食品化学","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_relation_11":{"attribute_name":"著者 外部リンク","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"http://rns.nii.ac.jp/nr/1000070510874"}]}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"SATOI, KEIKO"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学・農学部・助教"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"里井,  恵子"},{"creatorName":"サトイ, ケイコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"3363","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"70510874","nameIdentifierScheme":"研究者番号","nameIdentifierURI":" "}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-17"}],"displaytype":"detail","filename":"KAKEN_20880030seika.pdf","filesize":[{"value":"344.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KAKEN_20880030seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/3076/files/KAKEN_20880030seika.pdf"},"version_id":"a74485fa-e934-45b0-a6a8-b826f679f9db"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"栄養生化学","subitem_subject_scheme":"Other"},{"subitem_subject":"栄養","subitem_subject_scheme":"Other"},{"subitem_subject":"循環器","subitem_subject_scheme":"Other"},{"subitem_subject":"高血圧","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"胎生期の栄養管理が生活習慣病モデルラットの血管機能と酸化ストレスに及ぼす影響","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"胎生期の栄養管理が生活習慣病モデルラットの血管機能と酸化ストレスに及ぼす影響"}]},"item_type_id":"8","owner":"3","path":["2699","2700"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-07-06"},"publish_date":"2010-07-06","publish_status":"0","recid":"3076","relation_version_is_last":true,"title":["胎生期の栄養管理が生活習慣病モデルラットの血管機能と酸化ストレスに及ぼす影響"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-21T01:47:26.871501+00:00"}