{"created":"2023-06-20T16:33:58.933711+00:00","id":3045,"links":{},"metadata":{"_buckets":{"deposit":"38334ddb-3768-49aa-af87-27170f2ce7e0"},"_deposit":{"created_by":3,"id":"3045","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3045"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00003045","sets":["14:2667:2695:2696","21:2669:2697:2698"]},"author_link":["3139"],"item_8_alternative_title_3":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Search for lipid accumulation inhibitory and lipid metabolismpromoting constituents from medicinal foods"}]},"item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-01-01","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"6","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費補助金研究成果報告書 (2009. )"}]}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"伝統・伝承薬物として薬用に供される一方で，食材としてあるいは料理の香味付けやスパイスなどの食用としても用いられる薬用食品素材について，脂肪蓄積抑制作用および脂肪代謝促進作用成分の探索を実施することを目的とする．その結果，キク科植物の西洋ハーブであるデイジーフラワーやタイ産ムクロジから中性脂質吸収抑制サポニンおよびベンケイソウ科植物である垂盆草からHepG2 細胞を用いた脂肪蓄積抑制作用メガスチグマン化合物などを見い出した．(英文） In order to investigate bioactive constituents from medicinal foods, we examined following extensive screening trials: (1) inhibitory effects on serum triglyceride (TG) elevation in olive oil-treated mice (2) TG accumulation inhibitory activity in HepG2 cells and TG metabolism-promoting activity in high glucose pretreated HepG2 cells, and (3) inhibitory effects on TNF--induced cytotoxicity in mouse primary cultured hepatocytes and/or L929 cells. As the results, (1) antihyperlipidemic saponin constituents were obtained from flowers of Bellis perennis and pericarps of Sapindus rarak, (2) lipid accumulation inhibitors were obtained from Sedum sarmentosum, and (3) TNF-sensitivity degradation principles were obtained from Boesenbergia rotunda, Punica granatum, Helichrysum arenarium, and Piper chaba.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目：若手研究（Ｂ）;研究期間：2008～2009;課題番号：20790022;研究分野：医歯薬学;科研費の分科・細目：薬学・化学系薬学　生薬・天然物化学","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_relation_11":{"attribute_name":"著者 外部リンク","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"http://rns.nii.ac.jp/nr/1000010340449"}]}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"MORIKAWA, TOSHIO"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学・薬学総合研究所・講師"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"森川,  敏生"},{"creatorName":"モリカワ, トシオ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"3139","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"10340449","nameIdentifierScheme":"研究者番号","nameIdentifierURI":" "}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-17"}],"displaytype":"detail","filename":"KAKEN_20790022seika.pdf","filesize":[{"value":"563.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KAKEN_20790022seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/3045/files/KAKEN_20790022seika.pdf"},"version_id":"f4a38203-8c26-48b5-bda2-2feaa2b2862b"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"薬用食品","subitem_subject_scheme":"Other"},{"subitem_subject":"脂肪蓄積抑制作用","subitem_subject_scheme":"Other"},{"subitem_subject":"脂肪代謝促進作用","subitem_subject_scheme":"Other"},{"subitem_subject":"メタボリックシンドローム","subitem_subject_scheme":"Other"},{"subitem_subject":"デイジーフラワー","subitem_subject_scheme":"Other"},{"subitem_subject":"Sapindus rarak","subitem_subject_scheme":"Other"},{"subitem_subject":"垂盆草","subitem_subject_scheme":"Other"},{"subitem_subject":"Piper chaba","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"薬用食品からの脂肪蓄積抑制および脂肪代謝促進作用成分の探索","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"薬用食品からの脂肪蓄積抑制および脂肪代謝促進作用成分の探索"}]},"item_type_id":"8","owner":"3","path":["2696","2698"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-06-30"},"publish_date":"2010-06-30","publish_status":"0","recid":"3045","relation_version_is_last":true,"title":["薬用食品からの脂肪蓄積抑制および脂肪代謝促進作用成分の探索"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-21T01:48:22.425814+00:00"}