{"created":"2023-06-20T16:33:57.352453+00:00","id":3016,"links":{},"metadata":{"_buckets":{"deposit":"37ff070f-b7f4-4354-8ffd-87c9a4843688"},"_deposit":{"created_by":3,"id":"3016","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3016"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00003016","sets":["14:2667:2701:2702"]},"author_link":["3267"],"item_8_alternative_title_3":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"A model of corneal endotheliitis"}]},"item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-01-01","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"5","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費補助金研究成果報告書 (2008. )"}]}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"培養ヒト角膜内皮細胞は、HSV-1 に対して感受性が高いことを確認した。角膜内皮炎が少ないのは低感受性によるものではなく前房内の免疫反応の役割が大きいと考えられた。培養角膜実質細胞ではCTGF の産生量はTGF-βの濃度依存性に増加した. またCTGFはTGF-βの存在下で角膜実質細胞におけるフィブロネクチンの産生に対して促進的に働き、角膜実質細胞におけるフィブロネクチンの産生に関与していると考えられた. しかしながら、α-SMA の産生および、コラーゲンゲルの収縮に対してはTGF-βの添加の有無に関わらず影響を与えなかった.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目：若手研究（B）;研究期間：2007～2008;課題番号：19791299;研究分野：医歯薬学;科研費の分科・細目：外科系臨床医学・眼科学","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_relation_11":{"attribute_name":"著者 外部リンク","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"http://rns.nii.ac.jp/nr/1000050399119"}]}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"SUGIOKA, KOJI"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学・医学部・助教"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"杉岡,  孝二"},{"creatorName":"スギオカ, コウジ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-17"}],"displaytype":"detail","filename":"KAKEN_19791299seika.pdf","filesize":[{"value":"566.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KAKEN_19791299seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/3016/files/KAKEN_19791299seika.pdf"},"version_id":"0205f7ef-e994-4c20-a5ec-7bc4928ca1e1"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"endotheliitis","subitem_subject_scheme":"Other"},{"subitem_subject":"HSV-1","subitem_subject_scheme":"Other"},{"subitem_subject":"wound healing","subitem_subject_scheme":"Other"},{"subitem_subject":"CTGF","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"ヒト培養角膜内皮細胞を用いた角膜内皮炎モデルの作成","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ヒト培養角膜内皮細胞を用いた角膜内皮炎モデルの作成"}]},"item_type_id":"8","owner":"3","path":["21","2702"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-01-16"},"publish_date":"2010-01-16","publish_status":"0","recid":"3016","relation_version_is_last":true,"title":["ヒト培養角膜内皮細胞を用いた角膜内皮炎モデルの作成"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-21T01:49:19.480931+00:00"}