{"created":"2023-06-20T16:50:48.683983+00:00","id":23369,"links":{},"metadata":{"_buckets":{"deposit":"dee1fd2f-35bb-4908-b118-7fae868ba9ab"},"_deposit":{"created_by":3,"id":"23369","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"23369"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00023369","sets":["14:2667:4819"]},"author_link":["3139","3135"],"control_number":"23369","item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"36","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費助成事業研究成果報告書 (2021)"}]}]},"item_8_description_25":{"attribute_name":"リンクURL","attribute_value_mlt":[{"subitem_description":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18K06726/","subitem_description_type":"Other"}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：伝統・伝承医薬学において薬用に供される天然資源のなかで，食用資源としても利用される素材から，糖および脂質代謝改善効果を有する機能性成分を探索する．すなわち，内臓脂肪蓄積を成因基盤とする糖尿病あるいは脂質異常症の予防およびそれらの初期症状の緩和に効果のある食用資源を探索し，その活性寄与成分を明らかにするなどの科学的評価を実施，エビデンスに基づいた新たな機能性食品あるいは植物性医薬品の候補素材の提案・開発を実践する．加えて，見いだした活性寄与成分をテンプレート（医薬シーズ）として，その全合成および類縁体合成・評価を実施し，新たな医薬候補物質の創製をめざす．\n研究成果の概要（英文）： To explore new functional ingredients for improve glucose and/or lipid metabolisms from natural resources used for medicinal purposdes in traditional and folk medicines as well as also used as edible resources. Thus, we searched for new bioactive constituents for preventing diabetes or dyslipidemia based on visceral fat accumulation and alleviating their early symptoms. In addition, we aim to bioactivity evaluate of the active constituents and propose and develop new functional food and phytopharmaceutical candidate ingredients based on the evidence. Furthermore, we also aim to create new candidates by synthesizing and evaluating the total synthesis and analogues of the active components as new seeds.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目：基盤研究(C); 研究期間：2018～2021; 課題番号：18K06726; 研究分野：生薬・天然物化学; 科研費の分化・細目：","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ(WEKO2)","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"},{"subitem_text_value":"研究分担者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Morikawa, Toshio"},{"subitem_text_language":"en","subitem_text_value":"Ninomiya, Kiyofumi"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学薬学総合研究所; 教授"},{"subitem_text_value":"就実大学薬学部; 教授"}]},"item_8_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"Kindai University"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"森川, 敏生"},{"creatorName":"モリカワ, トシオ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"3139","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"10340449","nameIdentifierScheme":"研究者番号","nameIdentifierURI":""}]},{"creatorNames":[{"creatorName":"二宮, 清文"},{"creatorName":"ニノミヤ, キヨフミ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"3135","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"10434862","nameIdentifierScheme":"研究者番号","nameIdentifierURI":""}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-12-05"}],"displaytype":"detail","filename":"18K06726seika.pdf","filesize":[{"value":"410.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"18K06726seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/23369/files/18K06726seika.pdf"},"version_id":"ca0ba95a-1dfd-4d50-aab0-eed4bcb89e8a"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"糖代謝改善効果","subitem_subject_scheme":"Other"},{"subitem_subject":"脂質代謝改善効果","subitem_subject_scheme":"Other"},{"subitem_subject":"食用資源","subitem_subject_scheme":"Other"},{"subitem_subject":"機能性成分","subitem_subject_scheme":"Other"},{"subitem_subject":"サラシア","subitem_subject_scheme":"Other"},{"subitem_subject":"カンカニクジュヨウ","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"食用資源からの糖・脂質代謝改善効果を有する機能性成分の探索","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"食用資源からの糖・脂質代謝改善効果を有する機能性成分の探索","subitem_title_language":"ja"},{"subitem_title":"Search for functional ingredients to improve glucose and/or lipid metabolism from edible resources","subitem_title_language":"en"}]},"item_type_id":"8","owner":"3","path":["4819"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-12-05"},"publish_date":"2022-12-05","publish_status":"0","recid":"23369","relation_version_is_last":true,"title":["食用資源からの糖・脂質代謝改善効果を有する機能性成分の探索"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-09-12T05:17:09.615609+00:00"}