{"created":"2023-06-20T16:50:00.036972+00:00","id":22389,"links":{},"metadata":{"_buckets":{"deposit":"0c812858-e8e0-4ada-af38-f7f960efc642"},"_deposit":{"created_by":3,"id":"22389","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"22389"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00022389","sets":["14:2667:4710"]},"author_link":["3295"],"item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"5","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費助成事業研究成果報告書 (2020)"}]}]},"item_8_description_25":{"attribute_name":"リンクURL","attribute_value_mlt":[{"subitem_description":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18K12046/ | https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18K12046/","subitem_description_type":"Other"}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：エラスチンは高純度で精製することが難しく，このことに起因してエラスチンを対象とした研究は非常に遅れており，バイオメディカル分野への応用も今後の課題であると認識されている．本研究では，エラスチン材料を用いた腱や靭帯の再建方法の開発を最終目的として，脊柱に存在する黄色靭帯組織の力学的特性やエラスチンの力学的寄与を定量的に検討するとともに，その特性を模倣したエラスチン含有材料の作製を試みた．実験の結果，現時点では靭帯組織の特性を完全には模倣できていないものの，オーダーが異なるということはなかった．今後は，他の材料との複合化などによって，強度や伸展性の向上を図っていくことが重要であると推察された．研究成果の概要（英文）：Pure molecular solution of elastin is hardly extracted due to its insolubility. From this reason, many basic characteristics of elastin have not been fully elucidated not only in the area of biochemistry and molecular biology but also in that of biomechanics and biomaterial. Our overall goal was to determine whether the external medication using biomimetic materials which include elastin ingredients is effective for the maintenance and improvement of the extensibility of biological soft tissues such as tendons, ligaments, and skins during healing process. Specifically, in the present study, we developed elastin-based materials having the same elastic moduli as those of soft tissues. The tensile strength and failure strain of the elastin materials were approximately 58% and 50% of those of yellow ligaments, indicative of the incomplete mimicking of biological soft tissues. Further studies should be conducted to improve the strength and extensibility of the elastin materials.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目：基盤研究(C);  研究期間：2018～2020;   課題番号：18K12046;   研究分野：バイオメカニクス;   科研費の分科・細目：","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Yamamoto, Ei"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学生物理工学部; 准教授"}]},"item_8_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"Kindai University"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"山本, 衛"},{"creatorName":"ヤマモト, エイ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"3295","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"00309270","nameIdentifierScheme":"研究者番号","nameIdentifierURI":" "}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-03-07"}],"displaytype":"detail","filename":"18K12046seika.pdf","filesize":[{"value":"398.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"18K12046seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/22389/files/18K12046seika.pdf"},"version_id":"787dee30-ed02-4eec-85bb-083d5787d00a"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"バイオメカニクス","subitem_subject_scheme":"Other"},{"subitem_subject":"エラスチン","subitem_subject_scheme":"Other"},{"subitem_subject":"生体軟組織","subitem_subject_scheme":"Other"},{"subitem_subject":"腱","subitem_subject_scheme":"Other"},{"subitem_subject":"靭帯","subitem_subject_scheme":"Other"},{"subitem_subject":"力学的特性","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"エラスチン成分に着目した項靭帯および黄色靭帯の力学的評価と靭帯骨化症の治療法探索","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"エラスチン成分に着目した項靭帯および黄色靭帯の力学的評価と靭帯骨化症の治療法探索"},{"subitem_title":"Biomechanical evaluation of the nuchal and yellow ligaments considering elastin components and development of a new treatment for the ossification of vertebral ligaments","subitem_title_language":"en"}]},"item_type_id":"8","owner":"3","path":["4710"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-03-07"},"publish_date":"2022-03-07","publish_status":"0","recid":"22389","relation_version_is_last":true,"title":["エラスチン成分に着目した項靭帯および黄色靭帯の力学的評価と靭帯骨化症の治療法探索"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-20T19:46:41.993227+00:00"}