{"created":"2023-06-20T16:49:18.994075+00:00","id":21511,"links":{},"metadata":{"_buckets":{"deposit":"22fc6b8a-f521-470c-81b6-4c9dca45db91"},"_deposit":{"created_by":3,"id":"21511","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"21511"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00021511","sets":["14:2667:4613"]},"author_link":["43179","43180","43181","43182","43183"],"control_number":"21511","item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"13","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費助成事業研究成果報告書 (2019)"}]}]},"item_8_description_25":{"attribute_name":"リンクURL","attribute_value_mlt":[{"subitem_description":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17H05026/","subitem_description_type":"Other"}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：ヒト腸内常在菌叢最優勢種および代表的な善玉菌であるビフィズス菌のポリアミン合成・輸送について網羅的に解析を行った。また、多くのヒトにおいてヒト腸内常在菌叢における最優勢の2門であるBacteroidetes門およびFirmicutes門を代表する菌種 (Bacteroides thetaiotaomicron, B. dorei,Enterococcus faecalis) の単菌あるいは複数菌にまたがるポリアミン代謝・輸送系を遺伝学的・生化学的に解析した。さらに環境中に著量のポリアミンを放出する腸内細菌であるP. mirabilisの新規ポリアミンエクスポーターを2種、スクリーニングした。研究成果の概要（英文）：A comprehensive analysis of polyamine synthesis and transport in the most dominant species of the human intestinal microbiota and Bifidobacteria, which are typical beneficial\\\nbacteria, was performed. Then, genetic and biochemical analysis of polyamine metabolism and transport systems in a single bacterium or spanning multiple bacteria in the phylum Bacteroidetes and Firmicutes, the two most dominant phylum in the human intestinal microbiota, was carried out.\\\nFurthermore, two novel polyamine exporters in P. mirabilis, an intestinal bacterium that releases significant amounts of polyamines into the environment, have been screened. These results will provide important basic scientific insights for optimizing polyamine concentrations in the intestinal lumen.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目：若手研究(A);  研究期間：2017～2019;   課題番号：17H05026;   研究分野：応用微生物学;   科研費の分科・細目：","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ(WEKO2)","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"},{"subitem_text_value":"研究協力者"},{"subitem_text_value":"研究協力者"},{"subitem_text_value":"研究協力者"},{"subitem_text_value":"研究協力者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Kurihara, Shin"},{"subitem_text_language":"en","subitem_text_value":"Onaka, Hiroyasu"},{"subitem_text_language":"en","subitem_text_value":"Shinya, Kazuo"},{"subitem_text_language":"en","subitem_text_value":"Matsumoto, Mitsuharu"},{"subitem_text_language":"en","subitem_text_value":"Okuda, Syujiro"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学生物理工学部; 講師"}]},"item_8_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"Kindai University"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"栗原, 新"},{"creatorName":"クリハラ, シン","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"尾仲, 宏康"},{"creatorName":"オナカ, ヒロヤス","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"新家, 一男"},{"creatorName":"シンヤ, カズオ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"松本, 光晴"},{"creatorName":"マツモト, ミツハル","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"奥田, 修二郎"},{"creatorName":"オクダ, シュウジロウ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-03-15"}],"displaytype":"detail","filename":"17H05026seika.pdf","filesize":[{"value":"159.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"17H05026seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/21511/files/17H05026seika.pdf"},"version_id":"09bd028b-4f1c-4ba9-b7bc-36d366d4b9bc"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"ポリアミン","subitem_subject_scheme":"Other"},{"subitem_subject":"ヒト腸内常在菌叢最優勢種","subitem_subject_scheme":"Other"},{"subitem_subject":"Bacteroides dorei","subitem_subject_scheme":"Other"},{"subitem_subject":"B. thetaiotaomicron","subitem_subject_scheme":"Other"},{"subitem_subject":"Enterococcus faecalis","subitem_subject_scheme":"Other"},{"subitem_subject":"腸内細菌の培養","subitem_subject_scheme":"Other"},{"subitem_subject":"腸内細菌の遺伝子操作","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"ヒト腸内細菌最優勢種の腸管内腔におけるポリアミン生産機構の遺伝学的解析","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ヒト腸内細菌最優勢種の腸管内腔におけるポリアミン生産機構の遺伝学的解析","subitem_title_language":"ja"},{"subitem_title":"Genetic analysis of polyamine production mechanism in the intestinal lumen of\\\\nthe dominant human intestinal bacteria","subitem_title_language":"en"}]},"item_type_id":"8","owner":"3","path":["4613"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-03-15"},"publish_date":"2021-03-15","publish_status":"0","recid":"21511","relation_version_is_last":true,"title":["ヒト腸内細菌最優勢種の腸管内腔におけるポリアミン生産機構の遺伝学的解析"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-09-14T06:43:59.700530+00:00"}