{"created":"2023-06-20T16:49:17.309968+00:00","id":21473,"links":{},"metadata":{"_buckets":{"deposit":"0ddbb851-a515-4ed6-b889-68807efd9197"},"_deposit":{"created_by":3,"id":"21473","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"21473"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00021473","sets":["14:2667:4613"]},"author_link":["43257"],"control_number":"21473","item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"7","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費助成事業研究成果報告書 (2019)"}]}]},"item_8_description_25":{"attribute_name":"リンクURL","attribute_value_mlt":[{"subitem_description":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17K17846/","subitem_description_type":"Other"}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：本研究では、飲酒の際に生じるアセトアルデヒドによるDNA損傷がどのように修復されているか理解することを目標に実験を行なった。その結果、アセトアルデヒドによる損傷を修復すると考えられている相同組換え経路の新規制御因子SWSAP1とFIGNL1を発見した。二者による制御の分子メカニズムと個体における役割を明らかにした。 研究成果の概要（英文）：As a consequence of the analysis of acetaldehyde- induced DNA damage, we found novel regulatory factors of homologous recombination, SWSAP1 and FIGNL1. We also revealed FIGNL1 has an activity to prevent homologous recombination. In addition, the regulation by these proteins is essential for spermatogenesis and oogenesis in mice.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目：若手研究(B);  研究期間：2017～2019;   課題番号：17K17846;   研究分野：分子生物学;   科研費の分科・細目：","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ(WEKO2)","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Matsuzaki, Kenichiro"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学農学部; 助教"}]},"item_8_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"Kindai University"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"松嵜, 健一郎"},{"creatorName":"マツザキ, ケンイチロウ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-03-15"}],"displaytype":"detail","filename":"17K17846seika.pdf","filesize":[{"value":"182.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"17K17846seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/21473/files/17K17846seika.pdf"},"version_id":"8953eb6f-9c1c-412e-8f99-61a1c8d7cd20"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"相同組換え","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"体の大部分を占める静止期細胞における、アルコール代謝によるDNA損傷と修復の解析","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"体の大部分を占める静止期細胞における、アルコール代謝によるDNA損傷と修復の解析","subitem_title_language":"ja"},{"subitem_title":"Analysis of the molecular mechanism to repair acetaldehyde-induced DNA damage","subitem_title_language":"en"}]},"item_type_id":"8","owner":"3","path":["4613"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-03-15"},"publish_date":"2021-03-15","publish_status":"0","recid":"21473","relation_version_is_last":true,"title":["体の大部分を占める静止期細胞における、アルコール代謝によるDNA損傷と修復の解析"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-09-13T07:49:33.696593+00:00"}