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〈研究論文〉酸化ストレスおよび肝障害下のヒト肝ガン由来細胞株HepG2 に対する食品成分の効果
https://kindai.repo.nii.ac.jp/records/21380
https://kindai.repo.nii.ac.jp/records/2138076e06f23-a23e-4733-a006-a7de641cac0a
| 名前 / ファイル | ライセンス | アクション |
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| Item type | ☆紀要論文 / Departmental Bulletin Paper(1) | |||||||||||||||||
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| 公開日 | 2021-03-05 | |||||||||||||||||
| タイトル | ||||||||||||||||||
| タイトル | 〈研究論文〉酸化ストレスおよび肝障害下のヒト肝ガン由来細胞株HepG2 に対する食品成分の効果 | |||||||||||||||||
| タイトル | ||||||||||||||||||
| タイトル | 〈Original Papers〉Effects of various food ingredients on oxidative stress and injury in HepG2 human hepatoma cell | |||||||||||||||||
| 言語 | en | |||||||||||||||||
| 著者 |
森, 淳輝
× 森, 淳輝
× 中西, 慧
× 山田, 康枝
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| 言語 | ||||||||||||||||||
| 言語 | jpn | |||||||||||||||||
| キーワード | ||||||||||||||||||
| 主題 | HepG2, Oxidative stress, Polyphenol, Acetaminophen | |||||||||||||||||
| 資源タイプ | ||||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||
| 資源タイプ | departmental bulletin paper | |||||||||||||||||
| 著者(英) | ||||||||||||||||||
| 言語 | en | |||||||||||||||||
| 値 | MORI,Junki | |||||||||||||||||
| 著者(英) | ||||||||||||||||||
| 言語 | en | |||||||||||||||||
| 値 | NAKANISHI,Kei | |||||||||||||||||
| 著者(英) | ||||||||||||||||||
| 言語 | en | |||||||||||||||||
| 値 | YAMADA,Yasue | |||||||||||||||||
| 著者 所属 | ||||||||||||||||||
| 値 | 近畿大学大学院システム工学研究科 | |||||||||||||||||
| 著者 所属 | ||||||||||||||||||
| 値 | 近畿大学大学院システム工学研究科 | |||||||||||||||||
| 著者 所属 | ||||||||||||||||||
| 値 | 近畿大学大学院システム工学研究科: 近畿大学工学部化学生命工学科 | |||||||||||||||||
| 著者所属(翻訳) | ||||||||||||||||||
| 値 | Graduate School of Systems Engineering, Kindai University | |||||||||||||||||
| 著者所属(翻訳) | ||||||||||||||||||
| 値 | Graduate School of Systems Engineering, Kindai University | |||||||||||||||||
| 著者所属(翻訳) | ||||||||||||||||||
| 値 | Graduate School of Systems Engineering, Kindai University: Department of Biotechnology and Chemistry, Faculty of Engineering,Kindai University | |||||||||||||||||
| 版 | ||||||||||||||||||
| 出版タイプ | NA | |||||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_be7fb7dd8ff6fe43 | |||||||||||||||||
| 出版者 名前 | ||||||||||||||||||
| 出版者 | 近畿大学工学部 | |||||||||||||||||
| 書誌情報 |
近畿大学工学部研究報告 en : Research reports of the Faculty of Engineering, Kindai University 号 54, p. 1-6, 発行日 2021-02-20 |
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| 収録物識別子タイプ | ISSN | |||||||||||||||||
| 収録物識別子 | 2434592X | |||||||||||||||||
| 抄録 | ||||||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||||||
| 内容記述 | [Abstract]The protective effects of ingredients contained in various foods on oxidative stress were examined using the human liver hepatocellular carcinoma cell line HepG2. The anti-oxidative effects of dipeptides, an amino acid, amines, sugars, and polyphenols of their anti-oxidative effect were examined in the presence of H2O2, ethanol (EtOH), acetaldehyde (AcH) and acetaminophen (APAP), which are known to cause liver injury. Two dipeptides, glutamylglutamic acid (EE) and α-asparltylgycine (α-DG) showed a protective effect against injury of HepG2 cells caused by EtOH, but not against injury of cells caused by H2O2 and AcH. L-theanine (tea) showed a protective effect against injury caused by EtOH, AcH and H2O2. α-Ethylglycoside (α-EG) and a-glycosylglycerol(α-GG), which have been reported to show a protective effect on liver injury, showed a protective effect against injury of HepG2 cells caused by EtOH. Isoamylamine showed a protective effect against injury caused by AcH. In polyphenols, baicalin and resveratrol showed protective effects against injury cells caused by AcH, H2O2 and APAP. Here, we reported the protective effects of ingredients contained in food against damage of HepG2 cells caused by H2O2, AcH, EtOH, and APAP. It has been shown that the protective effect depends on the ingredients and also on the stress conditions. | |||||||||||||||||
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| 内容記述タイプ | Other | |||||||||||||||||
| 内容記述 | application/pdf | |||||||||||||||||