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犬肝切除後におけるランゲルハンス島の機能的, 形態学的変化とGI療法による影響
https://kindai.repo.nii.ac.jp/records/2135
https://kindai.repo.nii.ac.jp/records/21355a790619-79d6-4aae-a9e6-3eb92d402b4d
| 名前 / ファイル | ライセンス | アクション |
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Thesis_Mek0143_19910315-0001.pdf (10.4 MB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||||||
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| 公開日 | 2012-06-12 | |||||||||
| タイトル | ||||||||||
| タイトル | 犬肝切除後におけるランゲルハンス島の機能的, 形態学的変化とGI療法による影響 | |||||||||
| その他（別言語等）のタイトル | ||||||||||
| その他のタイトル | Effect of glucagon and insulin on the histochemical and functional alternation the Langerhans islands after hepatectomy in dogs in | |||||||||
| 著者 |
金沢, 秀剛
× 金沢, 秀剛
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| 言語 | ||||||||||
| 言語 | jpn | |||||||||
| キーワード | ||||||||||
| 主題 | liver-pancreas relashionship, GI-therapy after partial hepatectomy, changes of Langerhans islet after partial hepatectomy, Langerhans islet with GI-therapy | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_46ec | |||||||||
| 資源タイプ | thesis | |||||||||
| 著者(英) | ||||||||||
| en | ||||||||||
| Kanazawa, Hidetaka | ||||||||||
| 著者 所属 | ||||||||||
| 近畿大学医学部第二外科学教室 | ||||||||||
| 著者所属(翻訳) | ||||||||||
| Second Department of Surgery, Kinki University School of Medicine | ||||||||||
| 版 | ||||||||||
| 出版タイプ | VoR | |||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
| 出版者 名前 | ||||||||||
| 出版者 | 近畿大学 | |||||||||
| 書誌情報 |
博士学位論文 en : Thesis or Dissertation p. 1-12, 発行日 1991-01-01 |
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| 抄録 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | [ABSTRACT] The importance of liver-pancreas relationship has been pointed out recently, and out laboratory reported hypertrophy of Langerhans islandsof dogs after partial hepatectomy. The effect of glucaon and insulin (GI therapy) on the islets in dogs was investigated to clarify the mechanism of this hypertrophy. In ac ontrol group, a forty-percent hepatectomy was carried out. One and four weeks after the surgery, 0.5g/kg of glucose was administered intravenously, and followed by a blood sampling from the portal vein to measure the changes of glucose, insulin, and glucagon, respectively. In addition, areal changes of the islets of Langerhans after the operation were measured with P AP technique. In a GI group, the same experiment as in the control group was done and 1 mg of glucagon and 2 iu/kg of insulin were administered every morning after the operation. The following results were obtained, 1) In the control group， portal plasma insulin level and insulin rlsponse were decreased one week after the surgery, and sizes of islets were enlarged four weeks after the surgery. 2) In the GI group，t here were no decrease in portal plasma insulin level and insulin response one week after the surgery, and no enlargement of the sizes of the islets four week after the surgery. 3) Changes in glucagon level and response was same as those of insulin. Glucose level and response showed no difference between the two groups. 4) According to these observations，g lucagon and insulin are exhausted one week after hepatectomy in dogs. 80 it seems to be necessary to provide gsucagon and insulin after hepatectomy. | |||||||||
| 内容記述 | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | 学位の種類：医学 学位授与年月日：1991/3/15 指導：久山, 健 教授, Director : Prof. Kuyama, Takeshi ) 報告番号：甲第185号 学内授与番号：医甲143 NDL書誌ID：000000239657 | |||||||||
| フォーマット | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | application/pdf | |||||||||
