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Changes in activity of substantia nigra pars reticulata neurons after middle cerebral artery occlusion in the rat
https://kindai.repo.nii.ac.jp/records/2126
https://kindai.repo.nii.ac.jp/records/2126cfcbbdd9-7fc5-45fe-b4bd-ee941ef052da
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
Thesis_Mek0154-19920319-0001.pdf (1.2 MB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||||||
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| 公開日 | 2011-12-09 | |||||||||
| タイトル | ||||||||||
| タイトル | Changes in activity of substantia nigra pars reticulata neurons after middle cerebral artery occlusion in the rat | |||||||||
| その他（別言語等）のタイトル | ||||||||||
| その他のタイトル | ラット中大脳動脈閉塞後にみられる黒質網様部ニューロンの活動性の変化 | |||||||||
| 著者 |
Asai, Toshiharu
× Asai, Toshiharu
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| 言語 | ||||||||||
| 言語 | eng | |||||||||
| キーワード | ||||||||||
| 主題 | substantia nigra pars reticulata, unit activity, MCA occlusion, disinhibition, hyperexcitation | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_46ec | |||||||||
| 資源タイプ | thesis | |||||||||
| 著者(英) | ||||||||||
| 言語 | en | |||||||||
| 値 | 朝井, 俊治 | |||||||||
| 著者 所属 | ||||||||||
| 値 | Graduate School, Kinki University Course of Medicine Department of Physiology | |||||||||
| 著者所属(翻訳) | ||||||||||
| 値 | 近畿大学大学院 医学研究科生理学系専攻 | |||||||||
| 版 | ||||||||||
| 出版タイプ | VoR | |||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
| 出版者 名前 | ||||||||||
| 出版者 | 近畿大学 | |||||||||
| 書誌情報 |
博士学位論文 en : Thesis or Dissertation p. 1-21, 発行日 1992-01-01 |
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| 抄録 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | [ABSTRACT] The spontaneous single unit activity of substantia nigra pars reticulata (SNR) neurons was studied in control and in ipsilateral middle cerebral artery (MCA) -occluded rats. The activity of MCA-occluded preparations was recorded in 3 groups; 1 hour, 24 hours, and 7 days after MCA occlusion. Activity was recorded extracellularly with glass microelectrodes and was analyzed using time interval histograms. In the control, half of theSNR units (47％) showed a regular firing pattern. There was no change 1 hour after MCA occlusion. After 24 hours and 7 days, however, there was increased SNR neuronal unit activity with irregular firing patterns (67％ and 57％, respectively), and a slightly decreased mean firing rate. In the MCA-occluded groups, no hyperexcited neurons at all were found in the SNR. Our results indicated that SNR neuronal degeneration accompanied by striatal ischemia does not depend simply on hyperexcitation due to a disinhibition mechanism. | |||||||||
| 内容記述 | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | 学位の種類：医学 学位授与年月日：1992/3/19 指導： 秩父, 志行 教授 (Director: Prof. Chichibu, Shiko) 報告番号：甲第201号 学内授与番号：医甲154 NDL書誌ID：000000266459 | |||||||||
| フォーマット | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | application/pdf | |||||||||
