{"created":"2023-06-20T16:33:13.521805+00:00","id":2111,"links":{},"metadata":{"_buckets":{"deposit":"dbb2c3b4-e126-406c-b388-e8b0279432a0"},"_deposit":{"created_by":3,"id":"2111","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"2111"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00002111","sets":["14:2529:2619:2629","21:2532:2621:2630"]},"author_link":["2277"],"item_7_alternative_title_3":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"A neurophysiological study of diabetic neuropaty with cold immersion"}]},"item_7_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1998-01-01","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"13","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"博士学位論文"},{"bibliographic_title":"Thesis or Dissertation","bibliographic_titleLang":"en"}]}]},"item_7_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"[抄録] 糖尿病患者の末梢神経機能異常の早期における病態を明らかにすることを目的として, 臨床的に神経障害を示す糖尿病患者(DM+群)と示さない患者(DM-群)および年齢を一致させた健常者について, 手指寒冷負荷を用いて正中神経知覚伝導機能ならびに皮膚血流量を検索した. 寒冷負荷前の測定ではDM+群では神経伝導速度, 活動電位振幅ともに健常者と差がみられたのに対してDM一群では差異がみられなかった. 寒冷負荷中では, DM+群の伝導速度の低下率が軽度で, またDM群何れにおいてもSAPの低下率が軽度であり, 虚血抵抗性が認められた. また健常者では負荷後の反応性振幅増大が顕著にみられたが, DM群では軽度であった. さらに健常群では虚血中の血流増大すなわち寒冷誘発血管拡張反応がみられたが, DM群では欠如していた. 回復過程では健常群はSAPと同様前値を大きく上回る血流増大がみられたが, DM-群ではその反応は遅れ, DM+群ではみられなかった. 糖尿病では早期より末梢循環障害が存在すること, また神経障害が虚血抵抗性および虚血後の反応性増大の減弱として早期より発現していることを明らかにした.","subitem_description_type":"Abstract"}]},"item_7_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"学位の種類：医学　　学位授与年月日：1998/3/24　　指導：高橋, 光雄 教授(Director: Prof. Takahashi, Mitsuo)　　報告番号：乙第351号　　学内授与番号：医601　　NDL書誌ID：000000324346","subitem_description_type":"Other"}]},"item_7_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_7_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_7_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Nishimoto, Kazuhiro"}]},"item_7_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学医学部 神経内科学教室"}]},"item_7_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"西本,  和弘"},{"creatorName":"ニシモト, カズヒロ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2277","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-17"}],"displaytype":"detail","filename":"Thesis_Me0601-19980324-0001.pdf","filesize":[{"value":"756.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Thesis_Me0601-19980324-0001.pdf","url":"https://kindai.repo.nii.ac.jp/record/2111/files/Thesis_Me0601-19980324-0001.pdf"},"version_id":"5c69673c-a738-4f07-b999-6f951b857074"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"diabetic neuropathy","subitem_subject_scheme":"Other"},{"subitem_subject":"ischemic tolerance","subitem_subject_scheme":"Other"},{"subitem_subject":"cold immersion","subitem_subject_scheme":"Other"},{"subitem_subject":"cold in duced vasodilatation","subitem_subject_scheme":"Other"},{"subitem_subject":"excitability after cold immersion","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"thesis","resourceuri":"http://purl.org/coar/resource_type/c_46ec"}]},"item_title":"糖尿病性末梢神経障害に対する寒冷負荷による神経生理学的検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"糖尿病性末梢神経障害に対する寒冷負荷による神経生理学的検討"}]},"item_type_id":"7","owner":"3","path":["2629","2630"],"pubdate":{"attribute_name":"公開日","attribute_value":"2011-12-03"},"publish_date":"2011-12-03","publish_status":"0","recid":"2111","relation_version_is_last":true,"title":["糖尿病性末梢神経障害に対する寒冷負荷による神経生理学的検討"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-21T02:16:08.957908+00:00"}