{"created":"2023-06-20T16:48:40.258204+00:00","id":20680,"links":{},"metadata":{"_buckets":{"deposit":"d3a9899f-97f0-4e0f-8cb8-614636747695"},"_deposit":{"created_by":3,"id":"20680","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"20680"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00020680","sets":["14:2667:4550"]},"author_link":["4274","4183","4167","30473","3301"],"control_number":"20680","item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"6","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費助成事業研究成果報告書 (2018)"}]}]},"item_8_description_25":{"attribute_name":"リンクURL","attribute_value_mlt":[{"subitem_description":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16H05466/","subitem_description_type":"Other"}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：腎細胞癌に対する新規マルチペプチドワクチン（CA9、VEGFR1、EPOR、PDL1、HIF1：5種類のターゲット分子）の開発に着手し、HLA-A2拘束性の新規ペプチドのうち一部（EPOR、PDL1、HIF1）を同定し、臨床的な有用性について検討中である。また、以前に開発したCA9およびVEGFR1ペプチドワクチンをあわせて、マルチペプチドワクチンを確立する予定である。研究成果の概要（英文）：We have been working on the development of new MHC-class-I restricted peptide vaccines for five independent therapeutic targets （CA9、VEGFR1、EPOR、PDL1、HIF1）and have identified a significant candidate a part of HLA-A2 restricted peptide vaccines (EPOR, PDL1 and HIF1). We are currently investigating their clinical relevance. Together with CA9 and VEGFR1 previously developed peptide vaccines, we will establish multi-peptide vaccination system using these five peptide vaccines.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目：基盤研究(B);  研究期間：2016～2018;   課題番号：16H05466;   研究分野：泌尿器腫瘍;   科研費の分科・細目：","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ(WEKO2)","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"},{"subitem_text_value":"研究分担者"},{"subitem_text_value":"研究分担者"},{"subitem_text_value":"研究分担者"},{"subitem_text_value":"研究分担者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Uemura, Hiritsugu"},{"subitem_text_language":"en","subitem_text_value":"YOSHIMURA, kazuhiro"},{"subitem_text_language":"en","subitem_text_value":"De Velasco, Marco"},{"subitem_text_language":"en","subitem_text_value":"HARADA, mamoru"},{"subitem_text_language":"en","subitem_text_value":"MINAMI, takafumi"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学医学部; 教授"},{"subitem_text_value":"近畿大学医学部; 教授"},{"subitem_text_value":"近畿大学医学部; 助教"},{"subitem_text_value":"島根大学学術研究院医学・看護学系; 教授"},{"subitem_text_value":"近畿大学医学部; 講師"}]},"item_8_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"Kindai University"},{"subitem_text_value":"Kindai University"},{"subitem_text_value":"Kindai University"},{"subitem_text_value":""},{"subitem_text_value":"Kindai University"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"植村, 天受"},{"creatorName":"ウエムラ, ヒロツグ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"4274","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"90213397","nameIdentifierScheme":"NRID","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?kw=90213397"}]},{"creatorNames":[{"creatorName":"吉村, 一宏"},{"creatorName":"ヨシムラ, カズヒロ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"4183","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"20283757","nameIdentifierScheme":"NRID","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?kw=20283757"}]},{"creatorNames":[{"creatorName":"デベラスコ, マルコ"},{"creatorName":"デベラスコ, マルコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"4167","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"20449838","nameIdentifierScheme":"NRID","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?kw=20449838"}]},{"creatorNames":[{"creatorName":"原田, 守"},{"creatorName":"ハラダ, マモル","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"30473","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"50260716","nameIdentifierScheme":"NRID","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?kw=50260716"}]},{"creatorNames":[{"creatorName":"南, 高文"},{"creatorName":"ミナミ, タカフミ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"3301","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"70340809","nameIdentifierScheme":"NRID","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/search/?kw=70340809"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-03-12"}],"displaytype":"detail","filename":"16H05466seika.pdf","filesize":[{"value":"196.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"16H05466seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/20680/files/16H05466seika.pdf"},"version_id":"6ccf8e75-5e31-4d9a-b11a-1503c5a69df6"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"腎細胞癌","subitem_subject_scheme":"Other"},{"subitem_subject":"がんワクチン","subitem_subject_scheme":"Other"},{"subitem_subject":"ペプチドワクチン","subitem_subject_scheme":"Other"},{"subitem_subject":"免疫療法","subitem_subject_scheme":"Other"},{"subitem_subject":"HLA-A2","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"腎細胞癌に対するHLA-A2拘束性マルチペプチドワクチンの開発","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"腎細胞癌に対するHLA-A2拘束性マルチペプチドワクチンの開発","subitem_title_language":"ja"},{"subitem_title":"Development of the HLA-A2 restricted multi-peptides vaccine for renal cell carcinoma","subitem_title_language":"en"}]},"item_type_id":"8","owner":"3","path":["4550"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2020-03-12"},"publish_date":"2020-03-12","publish_status":"0","recid":"20680","relation_version_is_last":true,"title":["腎細胞癌に対するHLA-A2拘束性マルチペプチドワクチンの開発"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-09-20T06:41:28.961865+00:00"}