{"created":"2023-06-20T16:48:37.566054+00:00","id":20620,"links":{},"metadata":{"_buckets":{"deposit":"4c78713d-5346-4541-8edc-cc3fd130516b"},"_deposit":{"created_by":3,"id":"20620","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"20620"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00020620","sets":["14:2667:4550"]},"author_link":["43125"],"control_number":"20620","item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"5","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費助成事業研究成果報告書 (2018)"}]}]},"item_8_description_25":{"attribute_name":"リンクURL","attribute_value_mlt":[{"subitem_description":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15K18840/","subitem_description_type":"Other"}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：含窒素複素環化合物は天然に広く存在し、医農薬品における重要な部分構造であるため、その効率的合成法の開発は重要である。本申請研究では、転位反応を利用した1,5-二置換テトラゾールと3-アシルインドールの合成に取り組み、各々新たな合成法を報告した。1,5-二置換テトラゾールの合成では室温条件下ケトキシムからBeckmann転位が進行する反応条件を見出した。本手法は官能基許容性にも優れ、多様な1,5-二置換テトラゾール類の合成を行えることを明らかにした。またカルコン類の転位反応を利用した3-アシルインドールの合成では、フリーデル-クラフツ反応では収率が低下するインドール類の合成を行うことができた。研究成果の概要（英文）：The development of efficient synthetic methods for nitrogen-containing heterocyclic compounds are important because they are widely present in nature and are important structures in biologically active compounds. In this research, we reported the synthesis of 1, 5-disubstituted tetrazoles and 3-acylindoles using rearrangement reactions in different methods. In the synthesis of 1,5-disubstituted tetrazoles, we found mild reaction conditions under which Beckmann rearrangement proceeds from ketoximes. This method is excellent in functional group tolerance, and various 1,5-disubstituted tetrazoles can be synthesized. In the synthesis of 3-acylindoles utilizing the rearrangement reaction of chalcones, several indoles were able to synthesize in one-pot methods.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目：若手研究(B);  研究期間：2015～2018;   課題番号：15K18840;   研究分野：有機合成化学;   科研費の分科・細目：","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ(WEKO2)","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"NAKAMURA, Akira"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学薬学部; 助教"}]},"item_8_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"Kindai University"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"中村, 光"},{"creatorName":"ナカムラ, アキラ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-03-12"}],"displaytype":"detail","filename":"15K18840seika.pdf","filesize":[{"value":"208.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"15K18840seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/20620/files/15K18840seika.pdf"},"version_id":"8ed52250-965b-4fea-97f5-653a6b73bb74"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"転位反応","subitem_subject_scheme":"Other"},{"subitem_subject":"複素環合成","subitem_subject_scheme":"Other"},{"subitem_subject":"テトラゾール","subitem_subject_scheme":"Other"},{"subitem_subject":"インドール","subitem_subject_scheme":"Other"},{"subitem_subject":"ベンゾフラン","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"アゾール類の多様な誘導体合成法の開発と機能性化合物合成への応用","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"アゾール類の多様な誘導体合成法の開発と機能性化合物合成への応用","subitem_title_language":"ja"},{"subitem_title":"Development of synthesis method of various azoles derivatives and application to the synthesis of functional compounds","subitem_title_language":"en"}]},"item_type_id":"8","owner":"3","path":["4550"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2020-03-12"},"publish_date":"2020-03-12","publish_status":"0","recid":"20620","relation_version_is_last":true,"title":["アゾール類の多様な誘導体合成法の開発と機能性化合物合成への応用"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-09-15T01:38:25.719055+00:00"}