| アイテムタイプ |
紀要論文 / departmental bulletin paper(1) |
| 公開日 |
2025-09-22 |
| タイトル |
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|
タイトル |
A light and electron microscopical study on the dynamics and the resolution of brain edema fluid around the infarction in rat brain |
|
言語 |
en |
| 作成者 |
Maekura, Shunji
Hattori, Hideyuki
Shimoto, Takashi
Kadota, Eiji
Hashimoto, Shigeo
|
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
infarction, ischemia, resolution, brain edema, peroxidase |
| 内容記述 |
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|
内容記述タイプ |
Abstract |
|
内容記述 |
In order to chronologically and morphologically examine the dynamics and the resolution of interstitial fluid after cerebral infarction, experimental cerebral ischemia was produced in rat brain by microsphere-embolization. The horseradish peroxidase (HRP) was injected into the cerebral cortex as the tracer of the interstitial fluid dynamics. In the control group, there was a regular pattern of tracer distribution as follows: The injected tracer spread to the subarachnoidal space of the brain surface through the subcortical white matter to the ventricle. In the ischemic group, "dense tracer distribution around the infarction focus" was observed in addition to the regular pattern of the tracer distribution mentioned above. Further the ultrastructures of the core and the periphery of the infarction focus were observed electron microscopically. The tracer was not seen in the ischemic core. In this area, the glial processes were significantly dilatated. There were no viable neurons. On the other hand, the tracer was revealed diffusely in the vascular basement membrane and the abluminal vesicles in the endothelium of the blood vessels around the focus. In these areas, the structure was considerably well-preserved except for only slight swelling of the astrocytic processes. Thus, the results suggested that, in the blood vessels around the ischemic focus, there was an active vesicular transport of the edema fluid from the brain into the blood stream. |
|
言語 |
en |
| 出版者 |
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|
出版者 |
The Kinki University Medical Association |
|
言語 |
en |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
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|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 収録物識別子 |
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収録物識別子タイプ |
PISSN |
|
収録物識別子 |
03866092 |
| 開始ページ |
|
|
開始ページ |
163 |
| 終了ページ |
|
|
終了ページ |
171 |
| 書誌情報 |
en : ACTA MEDICA KINKI UNIVERSITY
巻 13,
号 2,
p. 163-171,
発行日 1988-12
|
AA0050842X-19881200-0163.pdf (1.3 MB)
