| アイテムタイプ |
紀要論文 / departmental bulletin paper(1) |
| 公開日 |
2025-09-22 |
| タイトル |
|
|
タイトル |
A review on the properties and applications of perfluorocarbon emulsions |
|
言語 |
en |
| 作成者 |
Voynikov, Tencho
Nikolova, Irina
Suzuki, Aritomo
Higashino, Hideaki
Petkova, Maria
Mega, Noriko
|
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
perfluorochemicals, artificial blood substitutes, clinical application, diagnostics, adverse reactions |
| 内容記述 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Besides modified hemoglobin solutions, the other main group of preparations competing in the field of blood substitutes are synthetic perfluorochemical emulsions (PFC). Their ability to transport oxygen has proven to be successful by the virtually complete blood substitution of rats with FC-43 preparation. Following comprehensive and profound experimental trials with another emulsion, Fluosol-DA 20% (FDA), the next breakthrough came with clinical application. FDA was used in the treatment of acute anemia, cases of ischemia and hypoxia including that of the brain, PTCA, in the perfusion of transplantation organs, and others. Many of the adverse reactions caused by FDA 20% were found to result from complement activation provoked by the emulsifier, Pluoronic F-68. The latest generation PFC emulsions are designed to be more safe and efficient. The application of some PFC preparations in diagnostics looks very promising. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
The Kinki University Medical Association |
|
言語 |
en |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 収録物識別子 |
|
|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
03866092 |
| 開始ページ |
|
|
開始ページ |
1 |
| 終了ページ |
|
|
終了ページ |
20 |
| 書誌情報 |
en : ACTA MEDICA KINKI UNIVERSITY
巻 15,
号 1,
p. 1-20,
発行日 1990-06
|
AA0050842X-19900600-0001.pdf (1.6 MB)
