| アイテムタイプ |
紀要論文 / departmental bulletin paper(1) |
| 公開日 |
2025-08-05 |
| タイトル |
|
|
タイトル |
Effects of various collagens and growth factors on proliferation of meningeal sarcoma cells (MS147) |
|
言語 |
en |
| 作成者 |
Nishida, Shozo
Akai, Fumiharu
Kim, Akio
Koezuka, Masahiro
Hashimoto, Shigeo
Tomura, T. Takanori
|
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
collagen gel culture, cell proliferation, meningeal sarcoma, MS147, collagen |
| 内容記述 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
We examined the effect of various collagen substrates and various growth factors on the proliferation of meningeal sarcoma (MS), transplanted to mice. The proliferation of cells was enhanced on plastic dishes coated with types I, III, and IV collagens, but not with type II collagen. The proliferation of cells in the collagen gel was higher than that on the collagen coated dishes, and was also enhanced by the addition of insulin, epidermal growth factor (EGF) and condition medium obtained from culture of 3T3 fibroblasts (CM(3T3)), but not by the addition of fibroblast growth factor (FGF) and platelet-derived growth factor (PDGF). The MS cell survived in transplanted mice, but the passage of MS cells was impossible on monolayer culture. However, in collagen gel culture, MS cells were subcultured for more than 35 generations. The influence of collagens and growth factors on the proliferation of MS cells presented specific characteristics that indicated that some three dimensional space or three dimensional intercellular adhesion may be essential to the survival and differentiation of MS cells, and suggested that collagen gel culture is a useful method for survival and passage of transplanted tumors (MS cells). |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
The Kinki University Medical Association |
|
言語 |
en |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 収録物識別子 |
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収録物識別子タイプ |
PISSN |
|
収録物識別子 |
03866092 |
| 開始ページ |
|
|
開始ページ |
35 |
| 終了ページ |
|
|
終了ページ |
39 |
| 書誌情報 |
en : ACTA MEDICA KINKI UNIVERSITY
巻 17,
号 1,
p. 35-39,
発行日 1992-06
|
AA0050842X-19920600-0035.pdf (311.5 KB)
