| アイテムタイプ |
紀要論文 / departmental bulletin paper(1) |
| 公開日 |
2025-08-06 |
| タイトル |
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|
タイトル |
Changes in M-CSF activity and CFU-GM- Inhibitory activity in the urine of patient with cyclic chronic myelogenous leukemia |
|
言語 |
en |
| 作成者 |
Urase, Fumiaki
Iwanaga, Takayuki
Tsuji, Kojiro
Hazu, Shizuka
Ishikawa, Hiroyuki
Ashida, Takashi
Tsubaki, Kazuo
Horiuchi, Atsushi
|
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
CML, cyclic fluctuation, urinary M-CSF, urinary CFU-GM-inhibitory activity |
| 内容記述 |
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|
内容記述タイプ |
Abstract |
|
内容記述 |
In the patient with chronic myelogenous leukemia (CML) exhibiting cyclic changes in peripheral blood leukocytes, changes in M-CSF and CFU-GM-inhibitory activity in the urine were studied. M-CSF activity in the urine was seen negatively correlated with peripheral blood monocyte count, and to increase prior to increases in peripheral monocytes. CFU-GM-inhibitory activity was high at the stage of increasing leukocytes and CFU-GM in peripheral blood as well as CFU-GM in bone marrow cells, but low at the stage of decreasing leukocytes. The number of CFU-GM in peripheral blood cells and in bone marrow cells in the decreasing leukocyte stage was lower than those levels found in common CML. These results indicate increased M-CSF activity and the consequent increase in monocytes to be closely related to the lesion of increasing leukocytes while CFU-GM-inhibitory activity seems more a negative regulator of the lesion of decreasing leukocytes. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
The Kinki University Medical Association |
|
言語 |
en |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 収録物識別子 |
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収録物識別子タイプ |
PISSN |
|
収録物識別子 |
03866092 |
| 開始ページ |
|
|
開始ページ |
145 |
| 終了ページ |
|
|
終了ページ |
153 |
| 書誌情報 |
en : ACTA MEDICA KINKI UNIVERSITY
巻 16,
号 2,
p. 145-153,
発行日 1991-11
|