| アイテムタイプ |
紀要論文 / departmental bulletin paper(1) |
| 公開日 |
2025-07-17 |
| タイトル |
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|
タイトル |
Coagulase types and toxin production of Staphylococcus aureus evaluated by drug susceptibility tests |
|
言語 |
en |
| 作成者 |
Nakamura, Yoshinobu
Furuta, Itaru
Obana, Yasuro
Ohata, Tsuneko
Yamazumi, Toshiaki
Kitahashi, Toshihiro
Ohba, Yasuhiro
|
| 言語 |
|
|
言語 |
eng |
| キーワード |
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|
主題 |
MRSA, coagulase types, enterotoxin, TSST-1 |
| 内容記述 |
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|
内容記述タイプ |
Abstract |
|
内容記述 |
We examined the susceptibility of Staphylococcus aureus (S. aureus), isolated at our hospital in 1991, to oxacillin (MPIPC), vancomycin (VCM), minocycline (MINO), flomoxef (FMOX), imipenem (IPM), tosufloxacin (TFLX), rifampicin (RFP), and arbekacin (ABK) by the microdilution technique. Isolates were considered to be methicillin-resistant S. aureus (MRSA) at a MIC (minimum inhibitory concentration) of MPI PC of 4 μg/ml or more. MRSA was classified according to the degree of resistance into Group II, IIIa, and IIIb. Methicillin-sensitive S. aureus (MSSA) was classified in Group I. Each group consisted of 50 strains. Coagulase types and toxin production were compared among the 4 groups. In Group I, the coagulase type varied widely from I to VIII, but coagulase type II (11/50 stains) and VII (15/50 strains) were detected relatively frequently. In GroupII, coagulase types II (22/50 strains) and III (20/50 strains) were detected. Groups IIIa and IIIb were primarily coagulase type II (49/50 and 46/50 strains, respectively). Enterotoxin was produced by 44% of the strains GroupI, 48% in GroupII, 88% in GroupIIIa, and 8% in GroupIIIb; the production rate was lowest in the markedly resistant GroupIIIb and highest in GroupIIIa. Toxic shock syndrome toxin-1 (TSST-1) was produced by 16% in Group I, 36% in GorupII, 86% in GroupIIIa, and 4% in GroupIIIb ; the production rate was also lowest in GroupIIIb. These results suggest that enterotoxin production is rather decreased in MRSA that have acquired high resistance. |
|
言語 |
en |
| 出版者 |
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|
出版者 |
The Kinki University Medical Association |
|
言語 |
en |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
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|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 収録物識別子 |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
03866092 |
| 開始ページ |
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|
開始ページ |
35 |
| 終了ページ |
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|
終了ページ |
41 |
| 書誌情報 |
en : ACTA MEDICA KINKI UNIVERSITY
巻 18,
号 1,
p. 35-41,
発行日 1993-06
|