| アイテムタイプ |
紀要論文 / departmental bulletin paper(1) |
| 公開日 |
2025-07-11 |
| タイトル |
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|
タイトル |
A case of cimetidine-induced transient depressed state in an elderly woman |
|
言語 |
en |
| 作成者 |
Hashimoto, Atsutaka
Makimura, Tomohiro
Hayashi, Ichiroh
Hukuya, Masato
Nakamura, Kimi
Yokouchi, Toshio
Yanai, Mika
|
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
cimetidine, depression, histamine receptor |
| 内容記述 |
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|
内容記述タイプ |
Abstract |
|
内容記述 |
A 77-year-old housewife presented with typical symptoms of depression associated with severe insomnia for ten days. Symptoms of depression included depressed mood, unhappiness, guilt, self-blame, feelings of worthlessness, hypochondriasis and suicidal ideation. Initially, we administered a regular dose of tricyclic anti-depressant, but this was not effective for these symptoms, including the profound idea of suicide. At that time, we found that the stomach medicine was cimetidine. The patient had been receiving this drug for 5 months proceeding the development of depression. Around one month after discontinuing the drug, the patient recovered dramatically from the depressed state. Previous reports on cimetidine-induced neuropsychiatric symptoms strongly suggest that the imbalance of H1 and H2 histamine neurotransmitters contributed most to the disturbance of normal mood. As this case shows, it is necessary to pay attention to the patient in a severely depressed state to whom cimetidine has been persistently administerd, particularly elderly people. Cimetidine should be discontinued before other treatment is attempted. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
The Kinki University Medical Association |
|
言語 |
en |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 収録物識別子 |
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収録物識別子タイプ |
PISSN |
|
収録物識別子 |
03866092 |
| 開始ページ |
|
|
開始ページ |
47 |
| 終了ページ |
|
|
終了ページ |
50 |
| 書誌情報 |
en : ACTA MEDICA KINKI UNIVERSITY
巻 19,
号 1,
p. 47-50,
発行日 1994-06
|
AA0050842X-19940600-0047.pdf (233.5 KB)
