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Increased regional myocardial blood flow in peri-infarct area during exercise-induced ST-segment elevation in canine myocardial infarction
https://kindai.repo.nii.ac.jp/records/2003064
https://kindai.repo.nii.ac.jp/records/200306443b9d371-2a9b-414b-95a6-3cad061681e9
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
AA0050842X-19960900-0245.pdf (1.3 MB)
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| Item type | 紀要論文 / departmental bulletin paper(1) | |||||||||||
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| 公開日 | 2025-07-07 | |||||||||||
| タイトル | ||||||||||||
| タイトル | Increased regional myocardial blood flow in peri-infarct area during exercise-induced ST-segment elevation in canine myocardial infarction | |||||||||||
| 言語 | en | |||||||||||
| 作成者 |
Shibutani, Toshiyuki
× Shibutani, Toshiyuki
× Miyazaki, Toshio
× Katori, Ryo
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| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
| キーワード | ||||||||||||
| 主題 | ST segment (elevation), exercise, myocardial infarction, myocardial blood flow | |||||||||||
| 内容記述 | ||||||||||||
| 内容記述タイプ | Abstract | |||||||||||
| 内容記述 | To examine the mechanism of exercise-induced ST-segment elevation in post myocardial infarction, we used a canine model of transmural myocardial infarction and measured regional myocardial blood flow with microspheres during exercise. Anterior myocardial infarction was created by embolization with a gelatin sponge in 9 dogs. The treadmill exercise tests on the fifth day after infarction caused a significant increase in the sum of ST-segment elevation in leads V2,V3,and V4 from 0.28±0.20 (mean±SD) to 0.60±0.23 mV (p<0.01). Myocardial blood flow increased significantly in the peri-infarct area (endocardial layer 0.36±0.34 to 0.77±0.66 ml/min/g, p<0.01,epicardial layer 0.52±0.24 to 1.02±0.55ml/min/g, p< 0.01). The endo/epi ratio remained at (0.65±0.37 to 0.67±0.49,ns). Coagulation necrosis extended to the epicardium. Myocardial blood flow in the infarcted area was limited, and did not change during exercise. We conclude that exercise-induced ST-segment elevation does not result from myocardial ischemia adjacent to the infarct area. The increase of myocardial blood flow suggests the enhancement of wall motion in the peri-infarct area during exercise. | |||||||||||
| 言語 | en | |||||||||||
| 出版者 | ||||||||||||
| 出版者 | The Kinki University Medical Association | |||||||||||
| 言語 | en | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| 資源タイプ | departmental bulletin paper | |||||||||||
| 出版タイプ | ||||||||||||
| 出版タイプ | AM | |||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||||
| 収録物識別子 | ||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||
| 収録物識別子 | 03866092 | |||||||||||
| 開始ページ | ||||||||||||
| 開始ページ | 245 | |||||||||||
| 終了ページ | ||||||||||||
| 終了ページ | 253 | |||||||||||
| 書誌情報 |
en : ACTA MEDICA KINKI UNIVERSITY 巻 21, 号 3, p. 245-253, 発行日 1996-09 |
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