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Use of cultured costal chondrocytes for the repair of defects in rabbit articular cartilage
https://kindai.repo.nii.ac.jp/records/2003041
https://kindai.repo.nii.ac.jp/records/200304155e0f9af-ac84-4688-ae3f-b40366250789
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
AA0050842X-19960300-0029.pdf (2.9 MB)
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| Item type | 紀要論文 / departmental bulletin paper(1) | |||||||||||
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| 公開日 | 2025-07-04 | |||||||||||
| タイトル | ||||||||||||
| タイトル | Use of cultured costal chondrocytes for the repair of defects in rabbit articular cartilage | |||||||||||
| 言語 | en | |||||||||||
| 作成者 |
Nishimoto, Shinsaku
× Nishimoto, Shinsaku
× Tan, Akihiro
× Tanaka, Seisuke
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| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
| キーワード | ||||||||||||
| 主題 | Transplantation, Cartilage, Collagen | |||||||||||
| 内容記述 | ||||||||||||
| 内容記述タイプ | Abstract | |||||||||||
| 内容記述 | For use in repair of articular cartilage defects, autografts were prepared by embedding and culturing cultured costal chondrocytes in collagen gels. We collected the outgrown chondrocytes from autogenous costal cartilage primarily cultured in a monolayer for 7 days to acquire a large number of cells. These cultured, costal chondrocytes were embedded into collagen gels and were further cultured for 10 days to acquire the appropriate hardness for use as autografts. In these autografts, the cell number increased two-fold and the cells incorporated 35S. At 18 days after the first surgery, autograft transplants were sized to fit defects, 5 mm in diameter, in rabbits extending to the depth of the subchondral bone in the patellar groove. Histological examination revealed that for 30 weeks after transplantation, the defects were covered with a hyaline-like cartilage. Biochemically, the repaired tissues possessed Type II collagen. Therefore, our results show that costal chondrocytes can be used for the purpose of repairing articular cartilage defects. | |||||||||||
| 言語 | en | |||||||||||
| 出版者 | ||||||||||||
| 出版者 | The Kinki University Medical Association | |||||||||||
| 言語 | en | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| 資源タイプ | departmental bulletin paper | |||||||||||
| 出版タイプ | ||||||||||||
| 出版タイプ | AM | |||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||||
| 収録物識別子 | ||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||
| 収録物識別子 | 03866092 | |||||||||||
| 開始ページ | ||||||||||||
| 開始ページ | 29 | |||||||||||
| 終了ページ | ||||||||||||
| 終了ページ | 38 | |||||||||||
| 書誌情報 |
en : ACTA MEDICA KINKI UNIVERSITY 巻 21, 号 1, p. 29-38, 発行日 1996-03 |
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