WEKO3
アイテム
Learning abilities in SHR and SHRSP in various water maze tasks
https://kindai.repo.nii.ac.jp/records/2002999
https://kindai.repo.nii.ac.jp/records/20029998e18f226-af02-4cdd-898b-192ea29d7547
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
AA0050842X-19970600-0159.pdf (1.0 MB)
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| アイテムタイプ | 紀要論文 / departmental bulletin paper(1) | |||||||
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| 公開日 | 2025-06-23 | |||||||
| タイトル | ||||||||
| タイトル | Learning abilities in SHR and SHRSP in various water maze tasks | |||||||
| 言語 | en | |||||||
| 作成者 |
Matsuo, Takuya
× Matsuo, Takuya
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| 言語 | ||||||||
| 言語 | eng | |||||||
| キーワード | ||||||||
| 主題 | acquisition learning, spatial learning, water maze, SHR, SHRSP, WKY | |||||||
| 内容記述 | ||||||||
| 内容記述タイプ | Abstract | |||||||
| 内容記述 | Several water maze tasks are widely used as tests for behavioral and learning abilities in teratology studies. Through such tasks many animals can be examined in a relatively short time using a simple apparatus without inflicting stress such as food deprivation in the growing period and electric shocks in escape learning tasks. The purpose of the present study was to investigate the learning ability of SHR, SHRSP and WKY mature male rats bred in our laboratory, by using several water maze tasks. SHR and SHRSP showed the more excellent learning abilities as indicated in the increase of rats with the correct response ratio in the single water T-, underwater T- and water E- maze tasks compared to WKY. In the Biel maze task, SHR showed an increase of the correct response ratio in comparison with SHRSP and WKY. In the Morris maze task, SHR and SHRSP showed a higher ability of the acquisition then WKY. In the probe trial, SHR and WKY stayed more frequently in the zone where the escape platform had been set, compared to SHRSP. In conclusion, SHR showed higher acquisition learning as compared to WKY in all water maze tasks. The spatial learining in the Morris maze task of SHR was similar to that of WKY. Though the learning ability of SHRSP was higher in acquisition trials as compared to WKY, at the water maze tasks except for the Biel maze, the spatial learning of SHRSP was lower than the other two strains. The acquisition learning tasks demonstrated behavioral characteristics associated with the hypertension in SHR and SHRSP. The lower spatial learning ability in SHRSP is considered to be due to dysfunction of the hippocampus caused by a circulatory disorder of the brain. These findings present the fundamental data for the water maze tasks in the behavioral and learning teratological studies using SHR and SHRSP. | |||||||
| 言語 | en | |||||||
| 出版者 | ||||||||
| 出版者 | The Kinki University Medical Association | |||||||
| 言語 | en | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | departmental bulletin paper | |||||||
| 出版タイプ | ||||||||
| 出版タイプ | AM | |||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||
| 収録物識別子 | ||||||||
| 収録物識別子タイプ | PISSN | |||||||
| 収録物識別子 | 03866092 | |||||||
| 開始ページ | ||||||||
| 開始ページ | 159 | |||||||
| 終了ページ | ||||||||
| 終了ページ | 171 | |||||||
| 書誌情報 |
en : ACTA MEDICA KINKI UNIVERSITY 巻 22, 号 2, p. 159-171, 発行日 1997-06 |
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