| アイテムタイプ |
紀要論文 / departmental bulletin paper(1) |
| 公開日 |
2025-06-20 |
| タイトル |
|
|
タイトル |
Azole resistant Candida albicans in a leukemic patient : a case report |
|
言語 |
en |
| 作成者 |
Yamazumi, Toshiaki
Kuroda, Takaya
Nishio, Hiroshi
Ohata, Tsuneko
Obana, Yasurou
Furuta, Itaru
Shirakawa, Chikara
Sumimoto, Yoshiyasu
Kanamaru, Akihisa
Horiuchi, Atsushi
|
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
Candida albicans, drug resistance, azole, leukemia |
| 内容記述 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
A 17-year-old male was diagnosed as having acute myelogenous leukemia. Therapy was not favorable and remission was not obtained. Occult blood was frequently detected and lower abdominal pain, diarrhea and melena appeared during the progression. Since Candida albicans were often isolated from fecal cultures and serological tests by CAND-TEC showed a positive reaction, the patient was diagnosed with intestinal candidiasis. Three series of 400mgs daily Fluconazole administration were performed, but there was no improvement. Using a series of strains isolated from this patient, the in vitro susceptibility and karyotype analysis using pulsed field gel electrophoresis were investigated retrospectively. The isolates were susceptible to azole agents in the early phase of the disease, but shifted to the resistant type during progression. In karyotype analysis, 4 subtypes were observed, and moreover, the types differed between azole-sensitive and azole-resistant strains. These differences indicated the mixed infection by both azole-sensitive and resistant strains. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
The Kinki University Medical Association |
|
言語 |
en |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 収録物識別子 |
|
|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
03866092 |
| 開始ページ |
|
|
開始ページ |
85 |
| 終了ページ |
|
|
終了ページ |
89 |
| 書誌情報 |
en : ACTA MEDICA KINKI UNIVERSITY
巻 23,
号 3/4,
p. 85-89,
発行日 1998-12
|
AA0050842X-19981200-0085.pdf (406.1 KB)
