| アイテムタイプ |
紀要論文 / departmental bulletin paper(1) |
| 公開日 |
2025-06-18 |
| タイトル |
|
|
タイトル |
T-lymphocyte subsets in patients with dilated cardiomyopathy and heart failure |
|
言語 |
en |
| 作成者 |
Imoto, Mayumi
Ishikawa, Kinji
Irimajiri, Kiyohiro
Akiyama, Toshiyuki
Ohba, Yasuhiro
Furuta, Itaru
|
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
T-lymphocyte subset, dilated cardiomyopathy, cardiac index |
| 内容記述 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
This study was conducted to elucidate the mechanisms of T-lymphocyte subset abnormalities in dilated cardiomyopathy. T-lymphocyte subsets (CD3, CD4, CD8, CD4/CD8) were measured in 20 patients with dilated cardiomyopathy and in 20 patients with congestive heart failure caused by various heart diseases, as well as 24 patients with hypertrophic cardiomyopathy, 10 with acute myocardial infarction, 13 with healed myocardial infarction, 5 with acute myocarditis, and 133 normal control subjects. Cardiac index, left ventricular end diastolic dimension, and left ventricular fractional shortening were measured. CD4 and CD8 lymphocytes were 1198±6, 697±4 in normal subjects, respectively. These were reduced to 776±38 (p<0.001), 479±24 (p<0.001) in heart disease patients as a whole. Reductions of CD4 and CD8 were most marked in patients with congestive heart failure, and was prominent in patients with dilated cardiomyopathy. CD3 and CD4 had positive correlations (r=0.961, p<0.01 ; r=0.923, p<0.01, respectively) with cardiac index, and CD8 had a negative correlation (r=-0.885, p<0.01) with left ventricular end diastolic dimension, indicating that T-lymphocyte subset abnormalities are elicited by impaired cardiac function and that observed reductions in CD4 and CD8 in dilated cardiomyopathy are secondary to impaired cardiac function. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
The Kinki University Medical Association |
|
言語 |
en |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 収録物識別子 |
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|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
03866092 |
| 開始ページ |
|
|
開始ページ |
13 |
| 終了ページ |
|
|
終了ページ |
17 |
| 書誌情報 |
en : ACTA MEDICA KINKI UNIVERSITY
巻 24,
号 1/2,
p. 13-17,
発行日 1999-06
|
AA0050842X-19990600-0013.pdf (410.5 KB)
