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Qualitative analysis of midband lipoproteins, remnant and lipoprotein(a), by agarose gel electrophoresis and differential staining of lipids
https://kindai.repo.nii.ac.jp/records/2002827
https://kindai.repo.nii.ac.jp/records/2002827c3911ccb-bd52-438f-a2c5-165583747845
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
AA0050842X-20041200-0031.pdf (800.2 KB)
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| アイテムタイプ | 紀要論文 / departmental bulletin paper(1) | |||||||
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| 公開日 | 2025-05-09 | |||||||
| タイトル | ||||||||
| タイトル | Qualitative analysis of midband lipoproteins, remnant and lipoprotein(a), by agarose gel electrophoresis and differential staining of lipids | |||||||
| 言語 | en | |||||||
| 作成者 |
Nishio, Hiroshi
× Nishio, Hiroshi
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| 言語 | ||||||||
| 言語 | eng | |||||||
| キーワード | ||||||||
| 主題 | midband lipoprotein, PAGE, agarose gel electrophoresis, remnant, IDL, Lp(a) | |||||||
| 内容記述 | ||||||||
| 内容記述タイプ | Abstract | |||||||
| 内容記述 | Objectives : Although midband lipoprotein, a heterogeneous fraction containing very low-density lipoprotein (VLDL)-remnant, lipoprotein(a) (Lp(a)), or modified low-density lipoprotein(LDL), promotes atherosclerosis, it is difficult to assess by conventional electrophoresis. This study aimed to assess the differences in lipid composition of midband lipoproteins. Design and Methods : Fifty subjects with midband lipoproteins detected by polyacrylamide gel electrophoresis (PAGE) were recruited and electrophoretic patterns were examined by a combined system of agarose gel electrophoresis and enzymatic stain of cholesterol (CHOL) and triglyceride (TG). Results : Subjects were divided into either a TG-rich midband group or a TG-poor midband group by a midband-CHOL/midband-TG ratio of 0.5 in this system. Lipid characteristics of the TG-rich midband group (ratio of <0.5) were similar to those of VLDL-remnant. The TG-poor midband group (ratio of >0.5) had a higher plasma Lp(a). Conclusion : This system was useful in analysis of the qualitative abnormalities of midband lipoproteins, particularly (we found) a midband-CHOL/midband-TG ratio of 0.5 may indicate the increase of VLDL-remnant or Lp(a). | |||||||
| 言語 | en | |||||||
| 出版者 | ||||||||
| 出版者 | The Kinki University Medical Association | |||||||
| 言語 | en | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | departmental bulletin paper | |||||||
| 出版タイプ | ||||||||
| 出版タイプ | AM | |||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||
| 収録物識別子 | ||||||||
| 収録物識別子タイプ | PISSN | |||||||
| 収録物識別子 | 03866092 | |||||||
| 開始ページ | ||||||||
| 開始ページ | 31 | |||||||
| 終了ページ | ||||||||
| 終了ページ | 38 | |||||||
| 書誌情報 |
en : ACTA MEDICA KINKI UNIVERSITY 巻 29, 号 2, p. 31-38, 発行日 2004-12 |
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