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気管支喘息患者多核白血球の気管支上皮細胞傷害性について：とくにComplement Receptor Type 3の関与について
https://kindai.repo.nii.ac.jp/records/2002626
https://kindai.repo.nii.ac.jp/records/200262657f30a45-c607-48bc-8f7a-6fcea16b39c3
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
AN00063584-19910625-0273.pdf (616.9 KB)
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| アイテムタイプ | ☆紀要論文 / Departmental Bulletin Paper(1) | |||||||||
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| 公開日 | 2025-03-24 | |||||||||
| タイトル | ||||||||||
| タイトル | 気管支喘息患者多核白血球の気管支上皮細胞傷害性について：とくにComplement Receptor Type 3の関与について | |||||||||
| 言語 | ja | |||||||||
| タイトル | ||||||||||
| タイトル | The polymorphonuclear leukocytes-mediated cytotoxicity against bronchial epithelial cells in bronchial asthma | |||||||||
| 言語 | en | |||||||||
| 著者 |
保川, 淳
× 保川, 淳
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| 言語 | ||||||||||
| 言語 | jpn | |||||||||
| キーワード | ||||||||||
| 主題 | bronchial asthma, polimorphonuclear leukocyte, bronchial epithelial cell, complement receptor type 3, natural cytotoxicity | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | departmental bulletin paper | |||||||||
| 出版タイプ | ||||||||||
| 出版タイプ | AM | |||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||
| 出版者 名前 | ||||||||||
| 出版者 | 近畿大学医学会 | |||||||||
| 言語 | ja | |||||||||
| bibliographic_information |
ja : 近畿大学医学雑誌 en : Medical Journal of Kinki University 巻 16, 号 2, p. 273-282, 発行日 1991-06-25 |
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| ISSN | ||||||||||
| 収録物識別子タイプ | PISSN | |||||||||
| 収録物識別子 | 03858367 | |||||||||
| 内容記述 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | Inflammation in the airway, which is caused by inflammatory cells including eosinophils and neutrophils, is related with the late asthmatic response and persistent airway hyperreactivity. The characteristics of polymorphonuclear leukocytes (PMN)-mediated natural cytotoxicity against bronchial epithelial cell line (AK-D) in bronchial asthma were investigated. PMN-mediated natural cytotoxicity in bronchial asthma was significantly greater than in normal subjects. The cytotoxicity was enhanced by stimulation of CR3 with the monoclonal anti-CR3 antibody of both patients with bronchial asthma and normal subjects. However, no enhancement with CR3 stimulation was observed in asthma attack patients. Moreover, when optimal doses of the monoclonal anti-CR3 antibody were used, no differences in CR3 expression were observed among these groups. However, when suboptimal doses were used, CR3 expression in patients with bronchial asthma during attack was weaker than in the normal subjects or the patients with asthma not during attack. | |||||||||
| 言語 | en | |||||||||
| 内容記述 | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | 本文データはCiNiiから複製したものである。 | |||||||||
| 言語 | ja | |||||||||
