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高血圧自然発症ラットにおける血圧と大動脈の自発性筋緊張との関係
https://kindai.repo.nii.ac.jp/records/2002537
https://kindai.repo.nii.ac.jp/records/2002537a29f81e2-dfc9-4b42-9ae5-077b327c2c0b
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
AN00063584-19911230-0033.pdf (174.3 KB)
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| Item type | ☆紀要論文 / Departmental Bulletin Paper(1) | |||||||||||||
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| 公開日 | 2025-03-04 | |||||||||||||
| タイトル | ||||||||||||||
| タイトル | 高血圧自然発症ラットにおける血圧と大動脈の自発性筋緊張との関係 | |||||||||||||
| 言語 | ja | |||||||||||||
| タイトル | ||||||||||||||
| タイトル | Blood pressure and spontaneous muscle tone in spontaneously hypertensive rats | |||||||||||||
| 言語 | en | |||||||||||||
| 著者 |
砂野, 哲
× 砂野, 哲
× 島村, 佳一
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| 言語 | ||||||||||||||
| 言語 | jpn | |||||||||||||
| キーワード | ||||||||||||||
| 主題 | intrinsic active tone, aorta, spontaneously hypertensive rats, extracellular Ca | |||||||||||||
| 資源タイプ | ||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||
| 資源タイプ | departmental bulletin paper | |||||||||||||
| 出版タイプ | ||||||||||||||
| 出版タイプ | AM | |||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||||||
| 出版者 名前 | ||||||||||||||
| 出版者 | 近畿大学医学会 | |||||||||||||
| 言語 | ja | |||||||||||||
| bibliographic_information |
ja : 近畿大学医学雑誌 en : Medical Journal of Kinki University 巻 16, 号 4補冊, p. 33-35, 発行日 1991-12-30 |
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| ISSN | ||||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||||
| 収録物識別子 | 03858367 | |||||||||||||
| 内容記述 | ||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||
| 内容記述 | Relation between spontaneous active tone and degree of hypertension was examined in aorta of spontaneously hypertensive rats. Isometric tension of ring preparation was recorded in normal physiological salt solution and tension change observed after removal of Ca was considered as extracellular Ca dependent spontaneous muscle tone. Marked intrinsic active tone was observed in endothelium-removed preparation from hypertensive rats. The tone was higher in hypertensive rats with a higher blood pressure, but low in preparations from normotensive rats. In endothelium-intact preparations from hypertensive rats, the height of the tone was decreased markedly, which indicates that the endothelium plays a role to inhibit spontaneous muscle tone. The relaxing ability of endothelium was impaired more in the preparation from the hypertensive rats with higher blood pressure. It is concluded that both the increase of spontaneous active tone and impairment of endothelium function can contribute to maintenance of high blood pressure in spontaneously hypertensive rats. | |||||||||||||
| 言語 | en | |||||||||||||
| 内容記述 | ||||||||||||||
| 内容記述タイプ | Other | |||||||||||||
| 内容記述 | 本文データはCiNiiから複製したものである。 | |||||||||||||
| 言語 | ja | |||||||||||||
