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  1. Public
  2. 研究紀要
  3. 医学雑誌
  4. 17(1)1992

虚血後心筋収縮障害と冠側副血流

https://kindai.repo.nii.ac.jp/records/2002462
https://kindai.repo.nii.ac.jp/records/2002462
1a7cab4f-7ed5-414e-afd1-8618e2f7c5ca
名前 / ファイル ライセンス アクション
AN00063584-19920325-0153.pdf AN00063584-19920325-0153.pdf (957.6 KB)
Item type ☆紀要論文 / Departmental Bulletin Paper(1)
公開日 2025-02-19
タイトル
タイトル 虚血後心筋収縮障害と冠側副血流
言語 ja
タイトル
タイトル Relationship between myocardial collateral flow and postischemic stunned myocardium in dogs
言語 en
著者 石田, 典裕

× 石田, 典裕

ja 石田, 典裕
近畿大学

en Ishida, Norihiro
Kinki University

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言語
言語 jpn
キーワード
主題 stunned myocardium, regional myocardial blood flow, non-radioactive colored microspheres, postextrasystolic potentiation
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ departmental bulletin paper
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
出版者 名前
出版者 近畿大学医学会
言語 ja
bibliographic_information ja : 近畿大学医学雑誌
en : Medical Journal of Kinki University

巻 17, 号 1, p. 153-173, 発行日 1992-03-25
ISSN
収録物識別子タイプ PISSN
収録物識別子 03858367
内容記述
内容記述タイプ Abstract
内容記述 This study was investigated the relationship between coronary collateral flow and myocardial contractile reserve estimated by postextrasystolic potentiation (PESP) in 13 open-chest dogs. The left anterior descending coronary artery was occluded for 15 minutes and reperfused for 240 minutes. Regional myocardial blood flow (RMBF) was measured using nonradioactive colored microspheres before and at 7 minutes after occlusion, as well as at 30, 60 and 240 minutes after reperfusion. Regional myocardial shortening was measured using ultrasonic crystals. During occlusion, RMBF was markedly reduced, but there was a considerable amount of flow, which was probably supplied by collaterals, to the ischemic myocardium. Systolic shortening (%SS) was reduced by coronary occlusion. The dogs were classified into the following 3 groups according to percent of control RMBF during coronary occlusion : group L, RMBF 20% or less ; group M, 21 to 70% ; and group H, 71% or more. In group L, %SS increased from 20.8±l.7% to 30.9±2.5% upon PESP before occlusion, while upon PESP for 5 min and 60 min after reperfusion it increased from 12.9±2.1% to 27.5±1.8% and from 14.2±1.9% to 32.0±1.8%, respectively. Before coronary occlusion, %SS with PESP and that without PESP showed high positive correlation (r=0.86, p<0.002). Fifteen minutes after coronary reperfusion, the ratio of %SS with PESP to that without PESP was inversely correlated with collateral blood flow (r=-0.45, p<0.05). In conclusion, increase of the systolic shortening by PESP was influenced by the degree of collateral flow during ischemia. In stunned myocardium, the contractile reserve induced by PESP was greater with low collateral flow than in with high flow.
言語 en
内容記述
内容記述タイプ Other
内容記述 本文データはCiNiiから複製したものである。
言語 ja
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